Formation of multi-armed spiral waves in neuronal network induced by adjusting ion channel conductance

doi:10.1142/S0217979215500435

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	Formation of multi-armed spiral waves in neuronal network induced by adjusting ion channel conductance
	Wang, Chunni; Ma, Jun; Hu, Bolin; Jin, Wuyin
刊名	INTERNATIONAL JOURNAL OF MODERN PHYSICS B
	2015-03-20
卷号	29 期号:7
关键词	Multi-armed spiral wave network of neurons ion channel blocking
ISSN号	0217-9792
DOI	10.1142/S0217979215500435
英文摘要	The Hodgkin-Huxley neuron model is used to describe the local dynamics of nodes in a two-dimensional regular network with nearest-neighbor connections. Multi-armed spiral waves emerge when a group of spiral waves rotate the same core synchronously. Here we have numerically investigated how multi-armed spiral waves are formed in such a system. Under the appropriate conditions, multi-armed spiral waves were able to develop as a result of adjusting the conductance of ion channels of particular neurons in the network. In a realistic neuron model, it can be practiced by blocking potassium of ion channels embedded in the membrane of neurons. For example, decreasing the potassium channel conductance in some neurons with a certain transient period can lead to the development of a group of double spirals in a localized area of the network. Furthermore, decreasing the excitability and the external forcing current to zero led to the growth of these double spirals and the formation of a stable multi-armed spiral wave that occupied the network under inhomogeneity.
资助项目	National Natural Science Foundation of China[11365014][11372122]
WOS研究方向	Physics
语种	英语
出版者	WORLD SCIENTIFIC PUBL CO PTE LTD
WOS记录号	WOS:000350650900005
状态	已发表
内容类型	期刊论文
源URL	[http://119.78.100.223/handle/2XXMBERH/34094]
专题	理学院机电工程学院
通讯作者	Ma, Jun
作者单位	Lanzhou Univ Technol, Dept Phys, Lanzhou 730050, Peoples R China
推荐引用方式 GB/T 7714	Wang, Chunni,Ma, Jun,Hu, Bolin,et al. Formation of multi-armed spiral waves in neuronal network induced by adjusting ion channel conductance[J]. INTERNATIONAL JOURNAL OF MODERN PHYSICS B,2015,29(7).
APA	Wang, Chunni,Ma, Jun,Hu, Bolin,&Jin, Wuyin.(2015).Formation of multi-armed spiral waves in neuronal network induced by adjusting ion channel conductance.INTERNATIONAL JOURNAL OF MODERN PHYSICS B,29(7).
MLA	Wang, Chunni,et al."Formation of multi-armed spiral waves in neuronal network induced by adjusting ion channel conductance".INTERNATIONAL JOURNAL OF MODERN PHYSICS B 29.7(2015).