Alteration in Resting-State EEG Microstates Following 24 Hours of Total Sleep Deprivation in Healthy Young Male Subjects

doi:10.3389/fnhum.2021.636252

	Alteration in Resting-State EEG Microstates Following 24 Hours of Total Sleep Deprivation in Healthy Young Male Subjects
	Ke, Ming 2; Li, Jianpan 1,2; Wang, Lubin 1
刊名	FRONTIERS IN HUMAN NEUROSCIENCE
	2021
卷号	15
关键词	sleep deprivation resting states electroencephalography topographical analysis EEG microstate
ISSN号	1662-5161
DOI	10.3389/fnhum.2021.636252
英文摘要	Purpose: The cognitive effects of total sleep deprivation (TSD) on the brain remain poorly understood. Electroencephalography (EEG) is a very useful tool for detecting spontaneous brain activity in the resting state. Quasi-stable electrical distributions, known as microstates, carry useful information about the dynamics of large-scale brain networks. In this study, microstate analysis was used to study changes in brain activity after 24 h of total sleep deprivation. Participants and Methods: Twenty-seven healthy volunteers were recruited and underwent EEG scans before and after 24 h of TSD. Microstate analysis was applied, and six microstate classes (A-F) were identified. Topographies and temporal parameters of the microstates were compared between the rested wakefulness (RW) and TSD conditions. Results: Microstate class A (a right-anterior to left-posterior orientation of the mapped field) showed lower global explained variance (GEV), frequency of occurrence, and time coverage in TSD than RW, whereas microstate class D (a fronto-central extreme location of the mapped field) displayed higher GEV, frequency of occurrence, and time coverage in TSD compared to RW. Moreover, subjective sleepiness was significantly negatively correlated with the microstate parameters of class A and positively correlated with the microstate parameters of class D. Transition analysis revealed that class B exhibited a higher probability of transition than did classes D and F in TSD compared to RW. Conclusion: The observation suggests alterations of the dynamic brain-state properties of TSD in healthy young male subjects, which may serve as system-level neural underpinnings for cognitive declines in sleep-deprived subjects.
WOS研究方向	Neurosciences & Neurology ; Psychology
语种	英语
出版者	FRONTIERS MEDIA SA
WOS记录号	WOS:000643708100001
内容类型	期刊论文
源URL	[http://ir.lut.edu.cn/handle/2XXMBERH/148261]
专题	计算机与通信学院
作者单位	1.Acad Mil Med Sci, Inst Mil Cognit & Brain Sci, Beijing, Peoples R China 2.Lanzhou Univ Technol, Coll Comp & Commun, Lanzhou, Gansu, Peoples R China;
推荐引用方式 GB/T 7714	Ke, Ming,Li, Jianpan,Wang, Lubin. Alteration in Resting-State EEG Microstates Following 24 Hours of Total Sleep Deprivation in Healthy Young Male Subjects[J]. FRONTIERS IN HUMAN NEUROSCIENCE,2021,15.
APA	Ke, Ming,Li, Jianpan,&Wang, Lubin.(2021).Alteration in Resting-State EEG Microstates Following 24 Hours of Total Sleep Deprivation in Healthy Young Male Subjects.FRONTIERS IN HUMAN NEUROSCIENCE,15.
MLA	Ke, Ming,et al."Alteration in Resting-State EEG Microstates Following 24 Hours of Total Sleep Deprivation in Healthy Young Male Subjects".FRONTIERS IN HUMAN NEUROSCIENCE 15(2021).