A kind of injectable Angelica sinensis polysaccharide(ASP)/hydroxyapatite (HAp) material for bone tissue engineering promoting vascularization, hematopoiesis, and osteogenesis in mice

doi:10.1080/00914037.2017.1320656

	A kind of injectable Angelica sinensis polysaccharide(ASP)/hydroxyapatite (HAp) material for bone tissue engineering promoting vascularization, hematopoiesis, and osteogenesis in mice
	Zhang, Weijie; Zhao, Lei; Ma, Jianzhong; Yang, Chenguang; Wang, Xiaochun; Pu, Xiuying; Wang, Yonggang; Ran, Fen; Wang, Yanling; Ma, Hui
刊名	INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
	2018
卷号	67 期号:4 页码:205-211
关键词	Angelica sinensis polysaccharide hematopoiesis hydroxyapatite osteogenesis vascularization
ISSN号	0091-4037
DOI	10.1080/00914037.2017.1320656
英文摘要	Scaffolds made from single hydroxyapatite (HAp) possess neither biological properties of bone nor functions of promoting vascularization and inhibiting immune rejection. To overcome these drawbacks of HAp, Angelica sinensis polysaccharide (ASP)/HAp composite scaffolds were prepared and its application possibility in bone tissue engineering was studied. The scaffolds were examined by mechanical test, releasing test, degradation test, and histological evaluation. The results showed that the scaffolds had good degradation and ASP releasing. The histological examination indicated that ASP/HAp material could effectively promote vascularization, hematopoiesis, and osteogenesis in mice. In conclusion, the composite material could be used for bone tissue engineering with good prospect.
WOS研究方向	Materials Science ; Polymer Science
语种	英语
出版者	TAYLOR & FRANCIS AS
WOS记录号	WOS:000428134700002
状态	已发表
内容类型	期刊论文
源URL	[http://119.78.100.223/handle/2XXMBERH/32839]
专题	生命科学与工程学院材料科学与工程学院
通讯作者	Zhang, Weijie
作者单位	Lanzhou Univ Technol, Sch Life Sci & Engn, Langongping Rd 287, Lanzhou, Gansu, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Weijie,Zhao, Lei,Ma, Jianzhong,et al. A kind of injectable Angelica sinensis polysaccharide(ASP)/hydroxyapatite (HAp) material for bone tissue engineering promoting vascularization, hematopoiesis, and osteogenesis in mice[J]. INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS,2018,67(4):205-211.
APA	Zhang, Weijie.,Zhao, Lei.,Ma, Jianzhong.,Yang, Chenguang.,Wang, Xiaochun.,...&Ma, Hui.(2018).A kind of injectable Angelica sinensis polysaccharide(ASP)/hydroxyapatite (HAp) material for bone tissue engineering promoting vascularization, hematopoiesis, and osteogenesis in mice.INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS,67(4),205-211.
MLA	Zhang, Weijie,et al."A kind of injectable Angelica sinensis polysaccharide(ASP)/hydroxyapatite (HAp) material for bone tissue engineering promoting vascularization, hematopoiesis, and osteogenesis in mice".INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS 67.4(2018):205-211.