A cone disk atomizer for production of biocompatible magnetic microcapsules for culture of anchorage-dependent mammalian cells

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	A cone disk atomizer for production of biocompatible magnetic microcapsules for culture of anchorage-dependent mammalian cells
	Lu, XJ; Cong, W; Ouyang, F
刊名	BIOTECHNOLOGY LETTERS
	2002-05-01
卷号	24 期号:10 页码:825-830
关键词	atomization cone-disk large-scale magnetic beads microcapsules
ISSN号	0141-5492
其他题名	Biotechnol. Lett.
中文摘要	A cone disk atomizer has been designed for preparation of gelatin/polystyrene magnetic microcapsules for use as microcarriers in anchorage-dependent mammalian cell culture. This apparatus facilitates continuous production of microcapsules and ignores surfactants or organic solvents in traditional emulsion. Compared with the flat-disk atomizer, the feeding flow is subjected to a normal pressure provided by the special cone-shaped disk and liquid slide is dramatically decreased in the cone-disk atomizer. A flow-rate-limitation is observed in both flat-disk atomization and cone-disk atomization. A 36% increase in flow-rate limitation was observed in cone-disk atomization than in flat-disk atomization indicating the potential of this method for large-scale preparations.
英文摘要	A cone disk atomizer has been designed for preparation of gelatin/polystyrene magnetic microcapsules for use as microcarriers in anchorage-dependent mammalian cell culture. This apparatus facilitates continuous production of microcapsules and ignores surfactants or organic solvents in traditional emulsion. Compared with the flat-disk atomizer, the feeding flow is subjected to a normal pressure provided by the special cone-shaped disk and liquid slide is dramatically decreased in the cone-disk atomizer. A flow-rate-limitation is observed in both flat-disk atomization and cone-disk atomization. A 36% increase in flow-rate limitation was observed in cone-disk atomization than in flat-disk atomization indicating the potential of this method for large-scale preparations.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Biotechnology & Applied Microbiology
研究领域[WOS]	Biotechnology & Applied Microbiology
收录类别	SCI
原文出处	://WOS:000175634500014
语种	英语
WOS记录号	WOS:000175634500014
公开日期	2013-11-12
内容类型	期刊论文
版本	出版稿
源URL	[http://ir.ipe.ac.cn/handle/122111/5630]
专题	过程工程研究所_研究所（批量导入）
作者单位	Chinese Acad Sci, Inst Proc Engn, Natl Lab Biochem Engn, Beijing 100080, Peoples R China
推荐引用方式 GB/T 7714	Lu, XJ,Cong, W,Ouyang, F. A cone disk atomizer for production of biocompatible magnetic microcapsules for culture of anchorage-dependent mammalian cells[J]. BIOTECHNOLOGY LETTERS,2002,24(10):825-830.
APA	Lu, XJ,Cong, W,&Ouyang, F.(2002).A cone disk atomizer for production of biocompatible magnetic microcapsules for culture of anchorage-dependent mammalian cells.BIOTECHNOLOGY LETTERS,24(10),825-830.
MLA	Lu, XJ,et al."A cone disk atomizer for production of biocompatible magnetic microcapsules for culture of anchorage-dependent mammalian cells".BIOTECHNOLOGY LETTERS 24.10(2002):825-830.