Bisabolane, cadinane, and cyclonerane sesquiterpenes from an algicolous strain of Trichoderma asperelloides

doi:10.1016/j.bioorg.2021.105223

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	Bisabolane, cadinane, and cyclonerane sesquiterpenes from an algicolous strain of Trichoderma asperelloides
	Zou, Ji-Xue 2,3; Song, Yin-Ping 3; Liu, Xiang-Hong 2,3; Li, Xiao-Nian 1; Ji, Nai-Yun 3
刊名	BIOORGANIC CHEMISTRY
	2021-10-01
卷号	115 页码:9
关键词	Trichoderma Sesquiterpene Bisabolane Cadinane Cyclonerane
ISSN号	0045-2068
DOI	10.1016/j.bioorg.2021.105223
通讯作者	Ji, Nai-Yun(nyji@yic.ac.cn)
英文摘要	Ten new bisabolane derivatives, trichobisabolins Q-Z (1-10), one new cadinane derivative, cadin-4-en-11-ol (11), and three new cyclonerane derivatives, cycloner-3-en-7,11-diol (12), isoepicyclonerodiol oxide (13), and norepicyclonerodiol oxide (14), were isolated from the endophytic fungal strain RR-dl-6-11 of Trichoderma asperelloides that was obtained from a marine alga. Their structures along with relative configurations were established mainly by NMR and IR as well as MS techniques, and the absolute configurations of 10 and 11 were assigned by ECD and X-ray diffraction data, respectively. Sesquiterpenes from the fungus T. asperelloides are reported for the first time. It is interesting that half of the bisabolane derivatives are demethylated. Compound 12 represents the first the occurrence of cyclopentenyl-bearing cycloneranes, and 14 seems a cyclopentyl-degrading cyclonerane derivative. Several isolates feature potent inhibition of marine phytoplankton species.
WOS关键词	METABOLITES ; HARZIANE
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
语种	英语
WOS记录号	WOS:000704133100007
资助机构	National Natural Science Foundation of China ; Taishan Scholar Project Special Funding
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/30765]
专题	海岸带生物学与生物资源利用重点实验室
通讯作者	Ji, Nai-Yun
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Megasci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
推荐引用方式 GB/T 7714	Zou, Ji-Xue,Song, Yin-Ping,Liu, Xiang-Hong,et al. Bisabolane, cadinane, and cyclonerane sesquiterpenes from an algicolous strain of Trichoderma asperelloides[J]. BIOORGANIC CHEMISTRY,2021,115:9.
APA	Zou, Ji-Xue,Song, Yin-Ping,Liu, Xiang-Hong,Li, Xiao-Nian,&Ji, Nai-Yun.(2021).Bisabolane, cadinane, and cyclonerane sesquiterpenes from an algicolous strain of Trichoderma asperelloides.BIOORGANIC CHEMISTRY,115,9.
MLA	Zou, Ji-Xue,et al."Bisabolane, cadinane, and cyclonerane sesquiterpenes from an algicolous strain of Trichoderma asperelloides".BIOORGANIC CHEMISTRY 115(2021):9.