Comparison of clinical features and 1-year outcomes between patients with psychotic disorder not otherwise specified and those with schizophrenia

doi:10.1111/eip.13276

	Comparison of clinical features and 1-year outcomes between patients with psychotic disorder not otherwise specified and those with schizophrenia
	Li, Ling 2,16; Rami, Fatima Zahra 2,16; Piao, Yan Hong 2,16; Lee, Bo Mi 2,16; Kim, Woo-Sung 2,16; Sui, Jing 3,4,5,10; Kim, Sung-Wan 11; Lee, Bong Ju 12; Kim, Jung Jin 13; Yu, Je-Chun 1
刊名	EARLY INTERVENTION IN PSYCHIATRY
	2022-02-06
页码	10
关键词	clinical staging diagnostic stability outcome psychotic disorder NOS
ISSN号	1751-7885
DOI	10.1111/eip.13276
通讯作者	Chung, Young Chul(chungyc@jbnu.ac.kr)
英文摘要	Aim: Research on psychotic disorder not otherwise specified (PNOS) that clearly mentions its subgroups is very rare. This study was conducted to identify the demographic and clinical features, cognitive function, and 1-year outcomes of patients with early stage PNOS compared with those with early stage schizophrenia (SZ). Methods: The study subjects were 54 and 321 patients with PNOS and SZ, respectively, who were registered at least more than 1 year ago. Due to drop out, only 37 and 210 patients with PNOS and SZ were evaluated at the 1-year follow-up. We compared clinical variables (duration of untreated psychosis, symptom severity, self-rating scales, and so on), cognitive function, and short-term outcomes (treatment response, remission, compliance, drop out, relapse) between the two groups. Results: The patients with PNOS were associated with higher diagnostic stability (53.7%) compared with those in previous studies. They had lower symptom severity, better treatment response at 2 months and higher remission rates at 12 months, but poorer compliance at 6 months compared with patients with SZ. Level of cognitive impairment in PNOS was intermediate between those of SZ patients and healthy controls. Conclusions: These findings indicate that PNOS has unique clinical features, suggesting that it should be treated as a distinct clinical syndrome. At the same time, however, prevention of its possible progression to other psychotic disorders in some patients with PNOS is also important.
资助项目	Korean Mental Health Technology R&D Project, Ministry of Health and Welfare, Republic of Korea[HL19C0015] ; Korea Health Industry Development Institute[HI18C2383]
WOS关键词	DIAGNOSTIC STABILITY ; DSM-IV ; PSYCHOMETRIC PROPERTIES ; 1ST EPISODE ; DEPRESSION ; RECOVERY ; VALIDITY ; SCALES ; BIRTH
WOS研究方向	Psychiatry
语种	英语
出版者	WILEY
WOS记录号	WOS:000751756700001
资助机构	Korean Mental Health Technology R&D Project, Ministry of Health and Welfare, Republic of Korea ; Korea Health Industry Development Institute
内容类型	期刊论文
源URL	[http://ir.ia.ac.cn/handle/173211/47611]
专题	自动化研究所_脑网络组研究中心
通讯作者	Chung, Young Chul
作者单位	1.Eulji Univ, Eulji Univ Hosp, Sch Med, Dept Psychiat, Daejeon, South Korea 2.Jeonbuk Natl Univ, Jeonbuk Natl Univ Hosp, Biomed Res Inst, Res Inst Clin Med, Jeonju, South Korea 3.Chinese Acad Sci, Brainnetome Ctr, Inst Automat, Beijing, Peoples R China 4.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing, Peoples R China 5.Univ Chinese Acad Sci, Beijing, Peoples R China 6.Seoul Natl Univ, Bundang Hosp, Dept Psychiat, Seongnam, South Korea 7.Natl Ctr Mental Hlth, Dept Social Psychiat & Rehabil, Seoul, South Korea 8.Korea Univ, Coll Med, Guro Hosp, Dept Psychiat, Seoul, South Korea 9.Inje Univ, Coll Med, Dept Psychiat, Goyang, South Korea 10.Chinese Acad Sci, CAS Ctr Excellence Brain Sci & Intelligence Techn, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Li, Ling,Rami, Fatima Zahra,Piao, Yan Hong,et al. Comparison of clinical features and 1-year outcomes between patients with psychotic disorder not otherwise specified and those with schizophrenia[J]. EARLY INTERVENTION IN PSYCHIATRY,2022:10.
APA	Li, Ling.,Rami, Fatima Zahra.,Piao, Yan Hong.,Lee, Bo Mi.,Kim, Woo-Sung.,...&Chung, Young Chul.(2022).Comparison of clinical features and 1-year outcomes between patients with psychotic disorder not otherwise specified and those with schizophrenia.EARLY INTERVENTION IN PSYCHIATRY,10.
MLA	Li, Ling,et al."Comparison of clinical features and 1-year outcomes between patients with psychotic disorder not otherwise specified and those with schizophrenia".EARLY INTERVENTION IN PSYCHIATRY (2022):10.