Depolymerization and conversion of lignin to value-added bioproducts by microbial and enzymatic catalysis

doi:10.1186/s13068-021-01934-w

	Depolymerization and conversion of lignin to value-added bioproducts by microbial and enzymatic catalysis
	Weng,Caihong 1,2; Peng,Xiaowei 1,2; Han,Yejun 1,2
刊名	Biotechnology for Biofuels
	2021-04-03
卷号	14 期号:1
关键词	Lignin Depolymerization Enzymatic degradation Lignin-derived aromatics Metabolic pathways Value-added bioproducts Biosynthesis
DOI	10.1186/s13068-021-01934-w
英文摘要	AbstractLignin, the most abundant renewable aromatic compound in nature, is an excellent feedstock for value-added bioproducts manufacturing; while the?intrinsic heterogeneity and recalcitrance of which hindered the efficient lignin biorefinery and utilization. Compared with chemical processing, bioprocessing with microbial?and enzymatic catalysis is a clean and efficient method?for lignin depolymerization and conversion. Generally,?lignin bioprocessing involves lignin decomposition to?lignin-based aromatics?via extracellular microbial enzymes and further converted to?value-added bioproducts through microbial metabolism. In the review, the most recent advances in degradation and conversion of?lignin?to value-added bioproducts catalyzed by microbes and enzymes were summarized.?The lignin-degrading microorganisms of white-rot fungi, brown-rot fungi, soft-rot fungi, and bacteria under aerobic and anaerobic conditions were comparatively analyzed. The catalytic metabolism of the microbial lignin-degrading enzymes of laccase, lignin peroxidase, manganese peroxidase, biphenyl bond cleavage enzyme, versatile peroxidase, and β-etherize was discussed. The microbial metabolic process of H-lignin, G-lignin, S-lignin based derivatives, protocatechuic acid, and catechol was reviewed. Lignin was depolymerized to?lignin-derived aromatic compounds?by the?secreted enzymes of?fungi and bacteria, and the?aromatics were converted to?value-added compounds through microbial catalysis and metabolic engineering. The review also proposes new insights for future work to overcome the?recalcitrance of?lignin and convert it to value-added bioproducts by microbial and enzymatic catalysis.
语种	英语
出版者	BioMed Central
WOS记录号	BMC:10.1186/S13068-021-01934-W
内容类型	期刊论文
源URL	[http://ir.ipe.ac.cn/handle/122111/47685]
专题	中国科学院过程工程研究所
通讯作者	Han,Yejun
作者单位	1.Chinese Academy of Sciences; National Key Laboratory of Biochemical Engineering, Institute of Process Engineering 2.University of Chinese Academy of Sciences; School of Chemical Engineering
推荐引用方式 GB/T 7714	Weng,Caihong,Peng,Xiaowei,Han,Yejun. Depolymerization and conversion of lignin to value-added bioproducts by microbial and enzymatic catalysis[J]. Biotechnology for Biofuels,2021,14(1).
APA	Weng,Caihong,Peng,Xiaowei,&Han,Yejun.(2021).Depolymerization and conversion of lignin to value-added bioproducts by microbial and enzymatic catalysis.Biotechnology for Biofuels,14(1).
MLA	Weng,Caihong,et al."Depolymerization and conversion of lignin to value-added bioproducts by microbial and enzymatic catalysis".Biotechnology for Biofuels 14.1(2021).