Defect-rich graphene stabilized atomically dispersed Cu-3 clusters with enhanced oxidase-like activity for antibacterial applications

doi:10.1016/j.apcatb.2021.120826

CORC > 金属研究所 > 中国科学院金属研究所

	Defect-rich graphene stabilized atomically dispersed Cu-3 clusters with enhanced oxidase-like activity for antibacterial applications
	Meng, FanChi 4,5; Peng, Mi 3,6,7; Chen, Yunlei 8; Cai, Xiangbin ; Huang, Fei 5; Yang, Lini 4; Liu, Xiao 4; Li, Tao 4; Wen, Xiaodong 2,8; Wang, Ning 9,10
刊名	APPLIED CATALYSIS B-ENVIRONMENTAL
	2022-02-01
卷号	301 页码:7
关键词	Atomic dispersion Cu cluster Defect-rich graphene Oxidase-like activity Antibacterial
ISSN号	0926-3373
DOI	10.1016/j.apcatb.2021.120826
通讯作者	Yang, Lini(lnyang@lnu.edu.cn) ; Xia, Lixin(lixinxia@lnu.edu.cn) ; Liu, Hongyang(liuhy@imr.ac.cn) ; Ma, Ding(dma@pku.edu.cn)
英文摘要	Nanozyme has attracted great attention due to its diverse enzymatic catalytic activities. But there are still challenges in constructing novel nanozyme with robust catalytic activity. Here, we report an atomically dispersed and fully exposed Cu-3 cluster stabilized on defect-rich nanodiamond-graphene hybrid support (Cu-3/ND@G) with unique active adsorption sites, which benefit the adsorption and cleavage of O-2, resulting in enhanced oxidase-like and antibacterial activity. The catalytic rate constant of Cu-3/ND@G (K-cat = 1.474 x 10(-1) s(-1)) is higher than those of previously reported copper single atom oxidase mimics (0.5 x 10(-3) s(-1)) and even the commercial Pt/C mimics (1.01 x 10(-2) s(-1)). DFT calculation revealed that the atomically dispersed Cu-3 cluster as active center significantly improves the oxidase-like activity, attributing to the easy dissociation of O-2 into reactive oxygen species (center dot OH). The atomically dispersed Cu-3 cluster with an antibacterial rate of 100% in the NaAc buffer presents its potential application in the field of antibacterial materials.
资助项目	National Natural Science Foundation of China[21773101] ; National Natural Science Foundation of China[21671089] ; National Natural Science Foundation of China[91845201] ; National Natural Science Foundation of China[21961160722] ; National Natural Science Foundation of China[22072162] ; National Natural Science Foundation of China[21725301] ; National Natural Science Foundation of China[21932002] ; National Natural Science Foundation of China[21821004] ; Liaoning Revitalization Talents Program[XLYC1807151] ; Liaoning Revitalization Talents Program[XLYC1907055] ; National Key R&D Program of China[2016YFA0204100] ; National Key R&D Program of China[2017YFB0602200] ; Guangxi Key Laboratory of Information Materials (Guilin University of Electronic Technology)[201016-K] ; Research Grants Council of Hong Kong[C6021-14E] ; Research Grants Council of Hong Kong[N_HKUST624/19] ; Research Grants Council of Hong Kong[16306818] ; Tencent Foundation
WOS研究方向	Chemistry ; Engineering
语种	英语
出版者	ELSEVIER
WOS记录号	WOS:000711979300006
资助机构	National Natural Science Foundation of China ; Liaoning Revitalization Talents Program ; National Key R&D Program of China ; Guangxi Key Laboratory of Information Materials (Guilin University of Electronic Technology) ; Research Grants Council of Hong Kong ; Tencent Foundation
内容类型	期刊论文
源URL	[http://ir.imr.ac.cn/handle/321006/167477]
专题	金属研究所_中国科学院金属研究所
通讯作者	Yang, Lini; Xia, Lixin; Liu, Hongyang; Ma, Ding
作者单位	1.Univ New Haven, Ctr Integrat Mat Discovery, Dept Chem & Chem Engn, 300 Boston Post Rd, West Haven, CT 06516 USA 2.Univ Chinese Acad Sci, 19A Yuanquan Rd, Beijing 100049, Peoples R China 3.Peking Univ, BIC ESAT, Beijing 100871, Peoples R China 4.Liaoning Univ, Dept Chem, 66 Congshan Rd, Shenyang 110036, Liaoning, Peoples R China 5.Chinese Acad Sci, Inst Met Res, Shenyang Natl Lab Mat Sci, Shenyang 110016, Peoples R China 6.Peking Univ, Coll Chem & Mol Engn, Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China 7.Peking Univ, Coll Engn, Beijing 100871, Peoples R China 8.Chinese Acad Sci, Inst Coal Chem, State Key Lab Coal Convers, Taiyuan 030001, Peoples R China 9.Hong Kong Univ Sci & Technol, Dept Phys, Kowloon, Clear Water Bay, Hong Kong, Peoples R China 10.Hong Kong Univ Sci & Technol, Ctr Quantum Mat, Kowloon, Clear Water Bay, Hong Kong, Peoples R China
推荐引用方式 GB/T 7714	Meng, FanChi,Peng, Mi,Chen, Yunlei,et al. Defect-rich graphene stabilized atomically dispersed Cu-3 clusters with enhanced oxidase-like activity for antibacterial applications[J]. APPLIED CATALYSIS B-ENVIRONMENTAL,2022,301:7.
APA	Meng, FanChi.,Peng, Mi.,Chen, Yunlei.,Cai, Xiangbin.,Huang, Fei.,...&Ma, Ding.(2022).Defect-rich graphene stabilized atomically dispersed Cu-3 clusters with enhanced oxidase-like activity for antibacterial applications.APPLIED CATALYSIS B-ENVIRONMENTAL,301,7.
MLA	Meng, FanChi,et al."Defect-rich graphene stabilized atomically dispersed Cu-3 clusters with enhanced oxidase-like activity for antibacterial applications".APPLIED CATALYSIS B-ENVIRONMENTAL 301(2022):7.