Glycogen Synthase Kinase 3 Gene Is Important in Growth and Molting of the Pacific White Shrimp Litopenaeus vannamei

doi:10.3389/fmars.2021.681966

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	Glycogen Synthase Kinase 3 Gene Is Important in Growth and Molting of the Pacific White Shrimp Litopenaeus vannamei
	Pang, Ying 1,2,3; Zhang, Xiaojun 1,2,3; Yuan, Jianbo 1,2,3; Zhang, Xiaoxi 1,2; Su, Manwen 2,3; Li, Fuhua 1,2,3
刊名	FRONTIERS IN MARINE SCIENCE
	2021-06-24
卷号	8 页码:12
关键词	glycogen synthase kinase 3 Litopenaeus vannamei growth molting structure and function
DOI	10.3389/fmars.2021.681966
通讯作者	Zhang, Xiaojun(xjzhang@qdio.ac.cn)
英文摘要	Glycogen synthase kinase 3 (GSK3) is a vital multifunctional molecule that is widely distributed in invertebrates and vertebrates. GSK3 is a highly conserved serine/threonine (Ser/Thr) protein kinase, which plays an important role in insulin, Wnt, and various signaling pathways. In this study, a GSK3 gene were identified in the genome of the Pacific white shrimp, Litopenaeus vannamei, and analyzed its gene structure, phylogeny, and expression profiles. The deduced LvGSK3 protein contains a highly conserved Ser/Thr protein kinase catalytic (S_TKc) domain, the LvGSK3 gene exhibited high expression in different early developmental stages, most adult tissues, and premolting stages. RNA interference of LvGSK3 significantly retarded the increment of body weight and affected the expressions of molting-related genes compared with control groups. These results will improve our understanding of the conserved structure and functions of the LvGSK3 gene and show potential applications of shrimp growth.
资助项目	National Key R&D Program of China[2018YFD0900404] ; National Key R&D Program of China[2018YFD0900103] ; National Natural Sciences Foundation of China[31972782] ; National Natural Sciences Foundation of China[41876167] ; National Natural Sciences Foundation of China[31672632] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDA24030105]
WOS研究方向	Environmental Sciences & Ecology ; Marine & Freshwater Biology
语种	英语
出版者	FRONTIERS MEDIA SA
WOS记录号	WOS:000668965900001
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/176963]
专题	海洋研究所_实验海洋生物学重点实验室
通讯作者	Zhang, Xiaojun
作者单位	1.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Mega Sci, CAS & Shandong Prov Key Lab Expt Marine Biol, Qingdao, Peoples R China 3.Univ Chinese Acad Sci, Coll Earth Sci, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Pang, Ying,Zhang, Xiaojun,Yuan, Jianbo,et al. Glycogen Synthase Kinase 3 Gene Is Important in Growth and Molting of the Pacific White Shrimp Litopenaeus vannamei[J]. FRONTIERS IN MARINE SCIENCE,2021,8:12.
APA	Pang, Ying,Zhang, Xiaojun,Yuan, Jianbo,Zhang, Xiaoxi,Su, Manwen,&Li, Fuhua.(2021).Glycogen Synthase Kinase 3 Gene Is Important in Growth and Molting of the Pacific White Shrimp Litopenaeus vannamei.FRONTIERS IN MARINE SCIENCE,8,12.
MLA	Pang, Ying,et al."Glycogen Synthase Kinase 3 Gene Is Important in Growth and Molting of the Pacific White Shrimp Litopenaeus vannamei".FRONTIERS IN MARINE SCIENCE 8(2021):12.