The toxicological impact of the sunscreen active ingredient octinoxate on the photosynthesis activity of Chlorella sp.

doi:10.1016/j.marenvres.2021.105469

CORC > 海洋研究所 > 中国科学院海洋研究所 > 实验海洋生物学重点实验室

	The toxicological impact of the sunscreen active ingredient octinoxate on the photosynthesis activity of Chlorella sp.
	Tian, Lin 1; Huang, Lei 1; Cui, Hongwu 4; Yang, Feifei 2; Li, Yongfu 1,3
刊名	MARINE ENVIRONMENTAL RESEARCH
	2021-10-01
卷号	171 页码:8
关键词	Octinoxate Toxicity Marine microalga Chlorella Photosynthesis
ISSN号	0141-1136
DOI	10.1016/j.marenvres.2021.105469
通讯作者	Huang, Lei(hl3716@ouc.edu.cn) ; Li, Yongfu(lyf_qingdao@126.com)
英文摘要	Products designed to filter ultraviolet (UV) light are responsible for growing levels of anthropogenic environmental contamination. Octinoxate (ONT) is among the most common UV filtering active ingredients in cosmetics and sunscreens. The present study was designed to evaluate the toxicological effects of ONT on the photosynthetic activity of the Chlorella species of marine microalgae. These analyses identified ONT as a potent phototoxicant, the effects of which were more pronounced upon light exposure relative to in the dark. Short-term ONT exposure had no effect on photosynthetic electron transport capacity in the dark but did significantly reduce the ribulose-1,5-bisphosphate carboxylase/oxygenase activity in Chlorella cells, suggesting that this compound can directly suppress the photosynthetic Calvin cycle. When cells were subsequently exposed to light, the disruption of this cycle resulted in an excess of excitation energy, in turn driving the excessive generation of reactive oxygen species (ROS). ROS-mediated disruption of cellular metabolism further aggravated this ONTinduced microalgal damage. As such, under natural light conditions, these microalgae cells are exposed to increased oxidative stress that impairs their growth and causes pigment bleaching. Restricting the utilization of ONT-containing sunscreens thus has the potential to better preserve the integrity of aquatic and terrestrial ecosystems.
资助项目	Marine S&T Fund of Shandong Province for Pilot National Laboratory for Marine Science and Tech-nology (Qingdao)[2018SDKJ0501-1] ; National Natural Science Foundation of China[32002411] ; Natural Science Foundation of the Jiangsu Higher Education Institutions of China[19KJB170010]
WOS研究方向	Environmental Sciences & Ecology ; Marine & Freshwater Biology ; Toxicology
语种	英语
出版者	ELSEVIER SCI LTD
WOS记录号	WOS:000701668100006
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/176544]
专题	海洋研究所_实验海洋生物学重点实验室
通讯作者	Huang, Lei; Li, Yongfu
作者单位	1.Ocean Univ China, Coll Environm Sci & Engn, Qingdao 266100, Peoples R China 2.Jiangsu Ocean Univ, Sch Ocean Engn, Lianyungang 222005, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Megasci, Inst Oceanol, CAS Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 4.Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, Qingdao 266071, Peoples R China
推荐引用方式 GB/T 7714	Tian, Lin,Huang, Lei,Cui, Hongwu,et al. The toxicological impact of the sunscreen active ingredient octinoxate on the photosynthesis activity of Chlorella sp.[J]. MARINE ENVIRONMENTAL RESEARCH,2021,171:8.
APA	Tian, Lin,Huang, Lei,Cui, Hongwu,Yang, Feifei,&Li, Yongfu.(2021).The toxicological impact of the sunscreen active ingredient octinoxate on the photosynthesis activity of Chlorella sp..MARINE ENVIRONMENTAL RESEARCH,171,8.
MLA	Tian, Lin,et al."The toxicological impact of the sunscreen active ingredient octinoxate on the photosynthesis activity of Chlorella sp.".MARINE ENVIRONMENTAL RESEARCH 171(2021):8.