The prevalence and clinical characteristics of diabetes mellitus in Chinese inpatients with chronic schizophrenia: a multicenter cross-sectional study | |
Wang, Yanni4; Zeng, Lingyun3; Chen, Lijuan2; Zhou, Xin1; Huo, Lijuan6; Wang, Tingwei4; Zhou, Yongjie3; Zhang, Xiangyang5 | |
刊名 | PEERJ |
2021-11-30 | |
通讯作者邮箱 | zhangxy@psych.ac.cn (xiang yang zhang ) |
卷号 | 9页码:12 |
关键词 | Schizophrenia Diabetes mellitus Prevalence China Clinical characteristics |
ISSN号 | 2167-8359 |
DOI | 10.7717/peerj.12553 |
产权排序 | 6 |
文献子类 | 实证研究 |
英文摘要 | Background. Diabetes mellitus (DM) is common among patients with schizophrenia. However, information on patients comorbid DM and schizophrenia is limited in China. The present study investigated the prevalence of DM and its clinical characteristics in Chinese inpatients with chronic schizophrenia. Methods. A cross-sectional study was performed in Chinese inpatients with chronic schizophrenia. Diagnosis of Diabetes was established using World Health Organization diagnostic criteria for diabetes mellitus (persistent fasting glucose levels >= 126 mg/dl or 2-h plasma glucose >= 200 mg/dL after a 75-g Oral Glucose Tolerance Test). Patients were also measured height, weight, waist circumference, hip circumference, triglyceride level, and cholesterol level. Patients' psychiatric symptoms were measured by the Positive and Negative Syndrome Scale (PANSS). Binary logistic regression analysis was performed to examine the associated demographic and clinical variables in chronic schizophrenia. Results. A total of 988 inpatients (64.6% male, average age of 47.19 +/- 12.55) was recruited. The prevalence of DM in Chinese patients with chronic schizophrenia was 13.8% (95% CI [11.6-15.9]%). Logistic regression analysis showed that overweight (OR = 1.90, 95% CI [1.20-3.03], p = 0.006), obesity (OR = 1.85, 95% CI [1.07-3.21], p = 0.028), comorbid hypertension (OR = 2.14, 95% CI [1.34-3.42], p = 0.002), and course of schizophrenia (OR = 1.03, 95% CI [1.01-1.06], p = 0.040) were significantly associated with the DM risk in patients with schizophrenia. Conclusion. The findings indicated that diabetes mellitus was non-negligible in patients with chronic schizophrenia. Patients with schizophrenia should be regularly monitored for DM. Overweight/obesity, long duration of schizophrenia, and comorbid hypertension possibly were risk factors for diabetes. |
收录类别 | SCI |
资助项目 | Sanming Project of Medicine in Shenzhen |
WOS关键词 | MAJOR DEPRESSIVE DISORDER ; METABOLIC SYNDROME ; RISK-FACTORS ; BIPOLAR DISORDER ; MENTAL-ILLNESS ; PEOPLE ; PREDICTORS ; MORTALITY |
WOS研究方向 | Science & Technology - Other Topics |
语种 | 英语 |
出版者 | PEERJ INC |
WOS记录号 | WOS:000728904900004 |
资助机构 | Sanming Project of Medicine in Shenzhen |
内容类型 | 期刊论文 |
源URL | [http://ir.psych.ac.cn/handle/311026/41391] |
专题 | 心理研究所_中国科学院心理健康重点实验室 |
通讯作者 | Zhou, Yongjie; Zhang, Xiangyang |
作者单位 | 1.China Univ Geosci, Res Ctr Psychol & Hlth Sci, Wuhan, Peoples R China 2.South Cent Univ Nationalities, Sch Literature Journalism & Commun, Wuhan, Peoples R China 3.Shenzhen Kangning Hosp, Dept Psychiat Rehabil, Shenzhen, Peoples R China 4.Sch Publ Hlth, Dept Maternal Child & Adolescent Hlth, Lanzhou, Peoples R China 5.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, Beijing, Peoples R China 6.Guangzhou Med Univ, Affiliated Brain Hosp, Dept Psychiat, Guangzhou, Peoples R China |
推荐引用方式 GB/T 7714 | Wang, Yanni,Zeng, Lingyun,Chen, Lijuan,et al. The prevalence and clinical characteristics of diabetes mellitus in Chinese inpatients with chronic schizophrenia: a multicenter cross-sectional study[J]. PEERJ,2021,9:12. |
APA | Wang, Yanni.,Zeng, Lingyun.,Chen, Lijuan.,Zhou, Xin.,Huo, Lijuan.,...&Zhang, Xiangyang.(2021).The prevalence and clinical characteristics of diabetes mellitus in Chinese inpatients with chronic schizophrenia: a multicenter cross-sectional study.PEERJ,9,12. |
MLA | Wang, Yanni,et al."The prevalence and clinical characteristics of diabetes mellitus in Chinese inpatients with chronic schizophrenia: a multicenter cross-sectional study".PEERJ 9(2021):12. |
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