The mechanism of pattern formation in the developing drosophila retina

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	The mechanism of pattern formation in the developing drosophila retina
	Sun QiCheng
刊名	SCIENCE IN CHINA SERIES C-LIFE SCIENCES
	2007-02-01
卷号	50 期号:1 页码:120-124
关键词	drosophila retina cone cell foam physics stability condition complex system
ISSN号	1006-9305
其他题名	Sci. China Ser. C-Life Sci.
中文摘要	The biological patterning of the drosophila retina in vivo has striking resemblance to liquid bubbles, in which the surface mechanics due to N-cadherin within a sub-group of retina cells can be mimicked by surface tension. In this work, the aggregating patterns were reasonably simplified into 21) clusters consisting of 2-6 identical bubbles confined within a shrinking boundary. By using a hybrid fluid dynamics model proposed for liquid foams, the aggregating process of 2-6 retina cells was studied. Assuming the minimal perimeter for patterning cells to be the condition of stability patterns, the stable converged patterns we simulated in this work are the same as the experimental observations. More importantly, a new pattern of 6 cells was obtained which was found physically more stable than the other two reported by Hayashi and Carthew([1]). Aggregating perimeters of cells, i.e. the surface energy, showed a good linear fit with the cell numbers.
英文摘要	The biological patterning of the drosophila retina in vivo has striking resemblance to liquid bubbles, in which the surface mechanics due to N-cadherin within a sub-group of retina cells can be mimicked by surface tension. In this work, the aggregating patterns were reasonably simplified into 21) clusters consisting of 2-6 identical bubbles confined within a shrinking boundary. By using a hybrid fluid dynamics model proposed for liquid foams, the aggregating process of 2-6 retina cells was studied. Assuming the minimal perimeter for patterning cells to be the condition of stability patterns, the stable converged patterns we simulated in this work are the same as the experimental observations. More importantly, a new pattern of 6 cells was obtained which was found physically more stable than the other two reported by Hayashi and Carthew([1]). Aggregating perimeters of cells, i.e. the surface energy, showed a good linear fit with the cell numbers.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Biology
研究领域[WOS]	Life Sciences & Biomedicine - Other Topics
关键词[WOS]	IDENTICAL BUBBLES ; LIQUID FOAMS ; 2 DIMENSIONS ; SIMULATIONS ; ADHESION ; CELLS
收录类别	SCI
原文出处	://WOS:000245146700017
语种	英语
WOS记录号	WOS:000245146700017
公开日期	2013-10-15
内容类型	期刊论文
版本	出版稿
源URL	[http://ir.ipe.ac.cn/handle/122111/3432]
专题	过程工程研究所_研究所（批量导入）
作者单位	Chinese Acad Sci, Inst Proc Engn, Beijing 100080, Peoples R China
推荐引用方式 GB/T 7714	Sun QiCheng. The mechanism of pattern formation in the developing drosophila retina[J]. SCIENCE IN CHINA SERIES C-LIFE SCIENCES,2007,50(1):120-124.
APA	Sun QiCheng.(2007).The mechanism of pattern formation in the developing drosophila retina.SCIENCE IN CHINA SERIES C-LIFE SCIENCES,50(1),120-124.
MLA	Sun QiCheng."The mechanism of pattern formation in the developing drosophila retina".SCIENCE IN CHINA SERIES C-LIFE SCIENCES 50.1(2007):120-124.