The Pattern and Function of DNA Methylation in Fungal Plant Pathogens

doi:10.3390/microorganisms8020227

CORC > 植物研究所 > 中国科学院植物研究所 > 中科院北方资源植物重点实验室

	The Pattern and Function of DNA Methylation in Fungal Plant Pathogens
	He, Chang 1; Zhang, Zhanquan 1; Li, Boqiang ; Tian, Shiping 1
刊名	MICROORGANISMS
	2020
卷号	8 期号:2
关键词	DNA methylation fungal plant pathogen development pathogenicity
DOI	10.3390/microorganisms8020227
文献子类	Review
英文摘要	To successfully infect plants and trigger disease, fungal plant pathogens use various strategies that are dependent on characteristics of their biology and genomes. Although pathogenic fungi are different from animals and plants in the genomic heritability, sequence feature, and epigenetic modification, an increasing number of phytopathogenic fungi have been demonstrated to share DNA methyltransferases (MTases) responsible for DNA methylation with animals and plants. Fungal plant pathogens predominantly possess four types of DNA MTase homologs, including DIM-2, DNMT1, DNMT5, and RID. Numerous studies have indicated that DNA methylation in phytopathogenic fungi mainly distributes in transposable elements (TEs), gene promoter regions, and the repetitive DNA sequences. As an important and heritable epigenetic modification, DNA methylation is associated with silencing of gene expression and transposon, and it is responsible for a wide range of biological phenomena in fungi. This review highlights the relevant reports and insights into the important roles of DNA methylation in the modulation of development, pathogenicity, and secondary metabolism of fungal plant pathogens. Recent evidences prove that there are massive links between DNA and histone methylation in fungi, and they commonly regulate fungal development and mycotoxin biosynthesis.
学科主题	Microbiology
电子版国际标准刊号	2076-2607
出版地	BASEL
WOS关键词	INDUCED POINT MUTATION ; BOTRYTIS-CINEREA ; CYTOSINE METHYLTRANSFERASE ; ENTOMOPATHOGENIC FUNGUS ; ASPERGILLUS-FLAVUS ; GENOME REVEALS ; VIRULENCE ; PH ; GENE ; INSIGHTS
WOS研究方向	Microbiology
语种	英语
出版者	MDPI
WOS记录号	WOS:000519618200083
资助机构	National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31930086, 31530057,31671910]
内容类型	期刊论文
源URL	[http://ir.ibcas.ac.cn/handle/2S10CLM1/21859]
专题	中科院北方资源植物重点实验室
作者单位	1.Chinese Acad Sci, Inst Bot, Key Lab Plant Resources, Beijing 100093, Peoples R China 2.Univ Chinese Acad Sci, Coll Life Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	He, Chang,Zhang, Zhanquan,Li, Boqiang,et al. The Pattern and Function of DNA Methylation in Fungal Plant Pathogens[J]. MICROORGANISMS,2020,8(2).
APA	He, Chang,Zhang, Zhanquan,Li, Boqiang,&Tian, Shiping.(2020).The Pattern and Function of DNA Methylation in Fungal Plant Pathogens.MICROORGANISMS,8(2).
MLA	He, Chang,et al."The Pattern and Function of DNA Methylation in Fungal Plant Pathogens".MICROORGANISMS 8.2(2020).