Simultaneous extraction and surface enhanced Raman spectroscopy detection for the rapid and reliable identification of nicotine released from snus products

doi:10.1039/d1ay01601f

	Simultaneous extraction and surface enhanced Raman spectroscopy detection for the rapid and reliable identification of nicotine released from snus products
	Tian, Yongfeng 4; Tang, Xianghu 1,2; Fu, Yaning 3; Shang, Shanzhai 4; Dong, Gaofeng 4; Li, Tinghua 4; Huang, Xingjiu 1,2; Zhu, Donglai 4
刊名	ANALYTICAL METHODS
	2021-12-02
卷号	13
ISSN号	1759-9660
DOI	10.1039/d1ay01601f
通讯作者	Tang, Xianghu(tangxh2011@iim.ac.cn) ; Zhu, Donglai(zhudl@ynzy-tobacco.com)
英文摘要	Surface enhanced Raman spectroscopy (SERS) is a highly sensitive analytical detection technique that provides unique chemical and structural information on target molecules. Here, simultaneous extraction and SERS detection of nicotine for the rapid and reliable identification of nicotine released from snus products were performed based on a nano-Au assembly hierarchy structure in the capillary. Based on this strategy, the time evolution of the concentrations of nicotine released from the snus products was measured. Through comparison of the intensities of the spectral peaks of the symmetrical breathing of the pyridine moiety of nicotine molecules, with the prolongation of time, the concentration of nicotine released decreased significantly, which is helpful for establishing a method for the rapid evaluation of the processing and selection of excipients of snus products, and provides a new idea for further study of the production of snus pouches and related tobacco products. Moreover, based on data fitting, it can be calculated that the concentration of nicotine in the extraction presented an obvious quadratic relationship with time, and the release of most of the nicotine in the snus pouch, which is held through the gums and palate, was basically completed after similar to 15 min. Such destruction-free simultaneous measurements of snus products are opening up new perspectives for further research about the impact of nicotinoids on smokers' health and cessation programs.
资助项目	National Major Scientific and Technological Special Project for Significant New Drugs Development[2018ZX09J18112] ; Presidential Foundation of Hefei Institutes of Physical Science, Chinese Academy of Sciences[YZJJZX202019]
WOS关键词	SERS ; CAPILLARIES ; NANOPARTICLES ; LIQUIDS ; SMOKE ; FE3+
WOS研究方向	Chemistry ; Food Science & Technology ; Spectroscopy
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000720972700001
资助机构	National Major Scientific and Technological Special Project for Significant New Drugs Development ; Presidential Foundation of Hefei Institutes of Physical Science, Chinese Academy of Sciences
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/126578]
专题	中国科学院合肥物质科学研究院
通讯作者	Tang, Xianghu; Zhu, Donglai
作者单位	1.Chinese Acad Sci, Inst Solid State Phys, HFIPS, Hefei 230031, Peoples R China 2.Univ Sci & Technol China, Hefei 230026, Anhui, Peoples R China 3.China Natl Tobacco Qual Supervis & Test Ctr, Zhengzhou 450001, Peoples R China 4.China Tobacco Yunnan Ind Co Ltd, Yunnan Key Lab Tobacco Chem, Technol Ctr, Kunming 650231, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Tian, Yongfeng,Tang, Xianghu,Fu, Yaning,et al. Simultaneous extraction and surface enhanced Raman spectroscopy detection for the rapid and reliable identification of nicotine released from snus products[J]. ANALYTICAL METHODS,2021,13.
APA	Tian, Yongfeng.,Tang, Xianghu.,Fu, Yaning.,Shang, Shanzhai.,Dong, Gaofeng.,...&Zhu, Donglai.(2021).Simultaneous extraction and surface enhanced Raman spectroscopy detection for the rapid and reliable identification of nicotine released from snus products.ANALYTICAL METHODS,13.
MLA	Tian, Yongfeng,et al."Simultaneous extraction and surface enhanced Raman spectroscopy detection for the rapid and reliable identification of nicotine released from snus products".ANALYTICAL METHODS 13(2021).