Genome-wide association studies for common diseases and complex traits

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	Genome-wide association studies for common diseases and complex traits
	Joel N. Hirschhorn ; Mark J. Daly
刊名	Nature Reviews Genetics
	2005
卷号	6 期号:x 页码:95-108
中文摘要	Genetic factors strongly affect susceptibility to common diseases and also influence disease-related quantitative traits. Identifying the relevant genes has been difficult, in part because each causal gene only makes a small contribution to overall heritability. Genetic association studies offer a potentially powerful approach for mapping causal genes with modest effects, but are limited because only a small number of genes can be studied at a time. Genome-wide association studies will soon become possible, and could open new frontiers in our understanding and treatment of disease. However, the execution and analysis of such studies will require great care.
公开日期	2013-10-10
内容类型	期刊论文
源URL	[http://ir.xtbg.org.cn/handle/353005/4692]
专题	西双版纳热带植物园_文献共享
推荐引用方式 GB/T 7714	Joel N. Hirschhorn,Mark J. Daly. Genome-wide association studies for common diseases and complex traits[J]. Nature Reviews Genetics,2005,6(x):95-108.
APA	Joel N. Hirschhorn,&Mark J. Daly.(2005).Genome-wide association studies for common diseases and complex traits.Nature Reviews Genetics,6(x),95-108.
MLA	Joel N. Hirschhorn,et al."Genome-wide association studies for common diseases and complex traits".Nature Reviews Genetics 6.x(2005):95-108.