Sinomenine activates astrocytic dopamine D2 receptors and alleviates neuroinflammatory injury via the CRYAB

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	Sinomenine activates astrocytic dopamine D2 receptors and alleviates neuroinflammatory injury via the CRYAB
	Jing Qiu 2; Zhongjun Yan 1; Kai Tao 1; Yansong Li 3; Yuqian Li 1; Jingchen Li 2; Yushu Dong 2; Dayun Feng 1; Huisheng Chen 2
刊名	Journal of Neuroinflammation
	2016
卷号	13 期号:1
ISSN号	1742-2094
其他题名	Sinomenine activates astrocytic dopamine D2 receptors and alleviates neuroinflammatory injury via the CRYAB
英文摘要	Astrocyte-mediated neuroinflammation plays a critical role in ischemic stroke-induced secondary cerebral injury. Previous studies have suggested that the dopamine D2 receptor (DRD2) acts as a key target in regulating the neuroinflammatory response. However, the underlying molecular mechanisms are still unknown, and effective DRD2 agonists are lacking. In the present study, we examined the anti-inflammatory and neuroprotective effects of sinomenine (Sino), a monomeric compound with potential immunoregulatory properties in nervous system.
语种	英语
内容类型	期刊论文
源URL	[http://ir.imr.ac.cn/handle/321006/159460]
专题	金属研究所_中国科学院金属研究所
作者单位	1.中国人民解放军第四军医大学 2.Institute of Metal Research, Chinese Academy of Sciences 3.The 463rd Hospital of PLA
推荐引用方式 GB/T 7714	Jing Qiu,Zhongjun Yan,Kai Tao,et al. Sinomenine activates astrocytic dopamine D2 receptors and alleviates neuroinflammatory injury via the CRYAB[J]. Journal of Neuroinflammation,2016,13(1).
APA	Jing Qiu.,Zhongjun Yan.,Kai Tao.,Yansong Li.,Yuqian Li.,...&Huisheng Chen.(2016).Sinomenine activates astrocytic dopamine D2 receptors and alleviates neuroinflammatory injury via the CRYAB.Journal of Neuroinflammation,13(1).
MLA	Jing Qiu,et al."Sinomenine activates astrocytic dopamine D2 receptors and alleviates neuroinflammatory injury via the CRYAB".Journal of Neuroinflammation 13.1(2016).