Visible Post-Data Analysis Protocol for Natural Mycotoxin Production

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 环境化学与生态毒理学国家重点实验室

	Visible Post-Data Analysis Protocol for Natural Mycotoxin Production
	Li, Yanshen; Qu, Jinyao; Lin, Yucheng; Lu, Guozhu; You, Yanli; Jiang, Guibin; Wu, Yongning
刊名	JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
	2020-09-02
卷号	68 期号:35 页码:9603-9611
关键词	visible post-data analysis natural production Alternaria mycotoxin molecular networking
ISSN号	0021-8561
英文摘要	Fungal natural products are routinely analyzed using target detection protocols by comparing to commercial standards. However, discovery of new products suffers from a lack of high-throughput analytical techniques. Post-data process techniques have become popular tools for natural product confirmations and mycotoxin family analysis. In this work, a visible post-data process procedure with MZmine, GNPS, and Xcalibur was used for efficient analysis of high-resolution mass spectrometry. Conjugated products were screened with an optimized diagnostic fragmentation filtering module in MZmine and further confirmed with Xcalibur by comparing to unconjugated commercial standards. MS/MS spectral data were processed and used to establish a feature based on a molecular networking map in GNPS (Global Natural Products Social Molecular Networking; https://gflps.ucsd.edu), for visualization of fungal natural product families. The results demonstrate the potential of combining MZmine-, GNPS-, and Xcalibur-based methods for visible analysis of fungal natural products.
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/44859]
专题	生态环境研究中心_环境化学与生态毒理学国家重点实验室
推荐引用方式 GB/T 7714	Li, Yanshen,Qu, Jinyao,Lin, Yucheng,et al. Visible Post-Data Analysis Protocol for Natural Mycotoxin Production[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2020,68(35):9603-9611.
APA	Li, Yanshen.,Qu, Jinyao.,Lin, Yucheng.,Lu, Guozhu.,You, Yanli.,...&Wu, Yongning.(2020).Visible Post-Data Analysis Protocol for Natural Mycotoxin Production.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,68(35),9603-9611.
MLA	Li, Yanshen,et al."Visible Post-Data Analysis Protocol for Natural Mycotoxin Production".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 68.35(2020):9603-9611.