Separation of beta-agonists in pork on a weak cation exchange column by HPLC with fluorescence detection

	Separation of beta-agonists in pork on a weak cation exchange column by HPLC with fluorescence detection
	Meng, Wenying 1; Wei, Jie 1; Luo, Xi 1; Zhang, Feifang 1; Yang, Bingcheng 1; Guo, Zhimou 2; Liang, Xinmiao 1,2
刊名	analytical methods
	2012-04-01
卷号	4 期号:4 页码:1163-1167
ISSN号	1759-9660
通讯作者	章飞芳 ; 郭志谋
产权排序	2,6
英文摘要	the separation of beta-agonists was performed for the first time on a silica-based weak cation exchange (wcx) stationary phase in which aqueous electrolyte solution with small amount of organic solvent was used as the mobile phase. compared to the organic solvent used in reverse phase hplc mode, the merits of using an aqueous mobile phase include unique selectivity, environment-friendly operation and reduced operation costs. the effective separation of four commonly used beta-agonists including salbutamol, terbutaline, metoprolol and ractopamine, were achieved with the mobile phase of 20 mm ammonium formate/acetonitrile (5%). the interference from the hydrophobic analytes could be easily eliminated due to their poor retention under this mode. the detection limits for the above analytes when fluorescence detection is employed were in the range of 3.55-8.32 mu g kg(-1) and the spiked recoveries for metoprolol for the spike sample reached about 83% and the relative standard deviation (rsd) was 4.7%.
学科主题	物理化学
WOS标题词	science & technology ; physical sciences ; life sciences & biomedicine ; technology
类目[WOS]	chemistry, analytical ; food science & technology ; spectroscopy
研究领域[WOS]	chemistry ; food science & technology ; spectroscopy
关键词[WOS]	capillary-electrophoresis ; liquid-chromatography ; clenbuterol ; ractopamine ; salbutamol ; urine ; swine ; microextraction ; spectrometry ; performance
收录类别	SCI
语种	英语
WOS记录号	WOS:000302175700045
公开日期	2013-10-11
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/117990]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
推荐引用方式 GB/T 7714	Meng, Wenying,Wei, Jie,Luo, Xi,et al. Separation of beta-agonists in pork on a weak cation exchange column by HPLC with fluorescence detection[J]. analytical methods,2012,4(4):1163-1167.
APA	Meng, Wenying.,Wei, Jie.,Luo, Xi.,Zhang, Feifang.,Yang, Bingcheng.,...&Liang, Xinmiao.(2012).Separation of beta-agonists in pork on a weak cation exchange column by HPLC with fluorescence detection.analytical methods,4(4),1163-1167.
MLA	Meng, Wenying,et al."Separation of beta-agonists in pork on a weak cation exchange column by HPLC with fluorescence detection".analytical methods 4.4(2012):1163-1167.