Isobaric cross-sequence labeling of peptides by using site-selective N-terminus dimethylation

	Isobaric cross-sequence labeling of peptides by using site-selective N-terminus dimethylation
	Qin, Hongqiang; Wang, Fangjun; Zhang, Yi; Hu, Zhengyan; Song, Chunxia; Wu, Ren'an; Ye, Mingliang; Zou, Hanfa
刊名	chemical communications
	2012
卷号	48 期号:50 页码:6265-6267
ISSN号	1359-7345
通讯作者	邹汉法
产权排序	1,1
英文摘要	highly site-selective dimethyl labeling of n-terminus of peptides has been obtained by adjusting the acidic strength of the reaction solution. and this selective labeling strategy combined with the use of different isotope formaldehyde reagents has been successfully used in the proteome quantification by using the isobaric peptide cross-sequence labeling method, which would play increasingly important roles in the clinical diagnosis, especially in the discovery of biomarkers for diseases.
学科主题	物理化学
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, multidisciplinary
研究领域[WOS]	chemistry
关键词[WOS]	organocatalytic reductive amination ; quantitative proteomics ; cleavage sites ; living cells ; protein
收录类别	SCI
语种	英语
WOS记录号	WOS:000304486800018
公开日期	2013-10-11
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/117941]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	Chinese Acad Sci, CAS Key Lab Separat Sci Analyt Chem, Natl Chromatog R&A Ctr, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
推荐引用方式 GB/T 7714	Qin, Hongqiang,Wang, Fangjun,Zhang, Yi,et al. Isobaric cross-sequence labeling of peptides by using site-selective N-terminus dimethylation[J]. chemical communications,2012,48(50):6265-6267.
APA	Qin, Hongqiang.,Wang, Fangjun.,Zhang, Yi.,Hu, Zhengyan.,Song, Chunxia.,...&Zou, Hanfa.(2012).Isobaric cross-sequence labeling of peptides by using site-selective N-terminus dimethylation.chemical communications,48(50),6265-6267.
MLA	Qin, Hongqiang,et al."Isobaric cross-sequence labeling of peptides by using site-selective N-terminus dimethylation".chemical communications 48.50(2012):6265-6267.