Phosphine-catalyzed dearomative (3+2) annulation of 2-nitrobenzofurans and nitrobenzothiophenes with allenoates

doi:10.1039/c9ob00775j

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	Phosphine-catalyzed dearomative (3+2) annulation of 2-nitrobenzofurans and nitrobenzothiophenes with allenoates
	Zhao, Jian-Qiang 3; Yang, Lei 2; You, Yong 3; Wang, Zhen-Hua 3; Xie, Ke-Xin 1; Zhang, Xiao-Mei 2; Xu, Xiao-Ying 2; Yuan, Wei-Cheng 2
刊名	ORGANIC & BIOMOLECULAR CHEMISTRY
	2019
卷号	17 期号:21 页码:5294-5304
ISSN号	1477-0520
DOI	10.1039/c9ob00775j
产权排序	3
文献子类	Article
英文摘要	An efficient Ph2PMe-catalyzed dearomative (3 + 2) annulation of 2-nitrobenzofurans, 2-nitrobenzothiophenes, and 3-nitrobenzothiophenes with allenoates has been developed. With the developed protocol, a series of structurally important cyclopenta[b] benzofurans and cyclopenta[b]benzothiophenes were obtained in good to excellent yields (up to 98%) under mild conditions. In addition, preparative-scale experiments and transformations were conducted to exemplify the synthetic utility. The asymmetric version of this dearomative (3 + 2) annulation reaction was tentatively investigated by using chiral phosphine catalysts.
学科主题	Chemistry & Analysis
URL标识	查看原文
WOS关键词	MORITA-BAYLIS-HILLMAN ; ASYMMETRIC DEAROMATIZATION ; ENANTIOSELECTIVE SYNTHESIS ; CYCLOADDITION REACTION ; 3-ISOTHIOCYANATO OXINDOLES ; SUBSTITUTED ALLENOATES ; NATURAL-PRODUCTS ; CASCADE REACTION ; ALLYL ALCOHOLS ; 3-NITROINDOLES
WOS研究方向	Chemistry
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000471015200014
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/30539]
专题	公共实验与分析中心
作者单位	1.Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610041, Sichuan, Peoples R China 2.Chinese Acad Sci, Chengdu Inst Organ Chem, Natl Engn Res Ctr Chiral Drugs, Chengdu 610041, Sichuan, Peoples R China; 3.Chengdu Univ, Inst Adv Study, Chengdu 610106, Sichuan, Peoples R China;
推荐引用方式 GB/T 7714	Zhao, Jian-Qiang,Yang, Lei,You, Yong,et al. Phosphine-catalyzed dearomative (3+2) annulation of 2-nitrobenzofurans and nitrobenzothiophenes with allenoates[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2019,17(21):5294-5304.
APA	Zhao, Jian-Qiang.,Yang, Lei.,You, Yong.,Wang, Zhen-Hua.,Xie, Ke-Xin.,...&Yuan, Wei-Cheng.(2019).Phosphine-catalyzed dearomative (3+2) annulation of 2-nitrobenzofurans and nitrobenzothiophenes with allenoates.ORGANIC & BIOMOLECULAR CHEMISTRY,17(21),5294-5304.
MLA	Zhao, Jian-Qiang,et al."Phosphine-catalyzed dearomative (3+2) annulation of 2-nitrobenzofurans and nitrobenzothiophenes with allenoates".ORGANIC & BIOMOLECULAR CHEMISTRY 17.21(2019):5294-5304.