4-Mercapto-phenylboronic Acid Functionalized Quartz Crystal Microbalances Sensor for the Determination of Sialic Acid

	4-Mercapto-phenylboronic Acid Functionalized Quartz Crystal Microbalances Sensor for the Determination of Sialic Acid
	Duan Shu-Jing 1; He Xi-Wen 1; Chen Lang-Xing 1; Zhang Yu-Kui 1,2
刊名	chemical journal of chinese universities-chinese
	2012-03-10
卷号	33 期号:3 页码:464-469
关键词	Quartz crystal microbalance(QCM) Sialic acid(SA) 4-Mercapto-phenylboronic acid(MPBA) Self-assembled
通讯作者	陈朗星 ; 张玉奎
产权排序	2,4
英文摘要	a novel gold-coated quartz crystal microbalance(qcm) sensor functionalized by 4-mercapto-phenylboronic acid(mpba) was fabricated for monitoring of sialic acid. the surface property of qcm sensor was characterized by scanning electron microscope. the density of mpba on the surface of qcm was calculated by the frequency change of qcm. the basic principle of the mpba-modified sensor is that boronic acid can form reversible covalent bonds with analytes containing cis-1,2-diols groups. the results show a linear response in the range of 0. 50-5. 0 mmol/l of sialic acid. the detection limit was 0. 15 mmol/l(n = 11) for sialic acid. and high recovery of 101. 7 for the spiked artificial urine sample was obtained.
学科主题	物理化学
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, multidisciplinary
研究领域[WOS]	chemistry
关键词[WOS]	phenylboronic acid ; molecular recognition ; saccharide sensor ; glycopeptides ; glycoproteins ; enrichment ; membrane ; silica ; rairs ; films
收录类别	SCI
语种	英语
WOS记录号	WOS:000302330800006
公开日期	2013-10-11
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/117753]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Nankai Univ, Coll Chem, Tianjin 300071, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116011, Peoples R China
推荐引用方式 GB/T 7714	Duan Shu-Jing,He Xi-Wen,Chen Lang-Xing,et al. 4-Mercapto-phenylboronic Acid Functionalized Quartz Crystal Microbalances Sensor for the Determination of Sialic Acid[J]. chemical journal of chinese universities-chinese,2012,33(3):464-469.
APA	Duan Shu-Jing,He Xi-Wen,Chen Lang-Xing,&Zhang Yu-Kui.(2012).4-Mercapto-phenylboronic Acid Functionalized Quartz Crystal Microbalances Sensor for the Determination of Sialic Acid.chemical journal of chinese universities-chinese,33(3),464-469.
MLA	Duan Shu-Jing,et al."4-Mercapto-phenylboronic Acid Functionalized Quartz Crystal Microbalances Sensor for the Determination of Sialic Acid".chemical journal of chinese universities-chinese 33.3(2012):464-469.