Activatable Rotor for Quantifying Lysosomal Viscosity in Living Cells

	Activatable Rotor for Quantifying Lysosomal Viscosity in Living Cells
	Wang, Lu 1; Xiao, Yi 1; Tian, Wenming 2; Deng, Liezheng 2
刊名	journal of the american chemical society
	2013-02-27
卷号	135 期号:8 页码:2903-2906
ISSN号	0002-7863
通讯作者	肖义
产权排序	2,3
英文摘要	we have developed lyso-v, the first fluorescent probe of lysosomal viscosity. because of its lysosome-actived fluorescence characteristics, lyso-v has proved to be an ideal lysosomal tracer with high spatial and temporal resolution under laser confocal microscopy. more importantly, lyso-v shows its practical applicability in real-time quantification of lysosomal viscosity changes in live cells through fluorescence lifetime imaging microscopy.
学科主题	物理化学
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, multidisciplinary
研究领域[WOS]	chemistry
关键词[WOS]	storage disorders ; molecular rotors ; live cells ; mechanisms ; diseases ; biology ; events ; enzyme ; sensor ; media
收录类别	SCI
语种	英语
WOS记录号	WOS:000315618900010
公开日期	2013-10-11
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/117525]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Mol React Dynam, Dalian 116023, Peoples R China
推荐引用方式 GB/T 7714	Wang, Lu,Xiao, Yi,Tian, Wenming,et al. Activatable Rotor for Quantifying Lysosomal Viscosity in Living Cells[J]. journal of the american chemical society,2013,135(8):2903-2906.
APA	Wang, Lu,Xiao, Yi,Tian, Wenming,&Deng, Liezheng.(2013).Activatable Rotor for Quantifying Lysosomal Viscosity in Living Cells.journal of the american chemical society,135(8),2903-2906.
MLA	Wang, Lu,et al."Activatable Rotor for Quantifying Lysosomal Viscosity in Living Cells".journal of the american chemical society 135.8(2013):2903-2906.