A review on analysis methods, source identification, and cancer risk evaluation of atmospheric polycyclic aromatic hydrocarbons

doi:10.1016/j.scitotenv.2021.147741

	A review on analysis methods, source identification, and cancer risk evaluation of atmospheric polycyclic aromatic hydrocarbons
	Famiyeh, Lord 2,3; Chen, Ke 3; Xu, Jingsha 4; Sun, Yong 3; Guo, Qingjun 2; Wang, Chengjun 5; Lv, Jungang 6; Tang, Yu-Ting 7; Yu, Huan 8; Snape, Collin 9
刊名	SCIENCE OF THE TOTAL ENVIRONMENT
	2021-10-01
卷号	789 页码:18
关键词	Polycyclic aromatic hydrocarbons Analysis methods Source identification Receptor models Compound-specific isotopic analysis Cancer risk evaluation
ISSN号	0048-9697
DOI	10.1016/j.scitotenv.2021.147741
通讯作者	Guo, Qingjun(guoqj@igsnrr.ac.cn) ; He, Jun(Jun.He@nottingham.edu.cn)
英文摘要	Polycyclic aromatic hydrocarbons (PAHs) have gained attention because of their environmental persistence and effects on ecosystems, animals, and human health. They are mutagenic, carcinogenic, and teratogenic. The review provides background knowledge about their sources, metabolism, temporal variations, and size distribution in atmospheric particulate matter. The review article briefly discusses the analytical methods suitable for the extraction, characterization, and quantification of nonpolar and polar PAHs, addressing the challenges. Herein, we discussed the molecular diagnostic ratios (DRs), stable carbon isotopic analysis (SCIA), and receptor models, with much emphasis on the positive matrix factorization (PMF) model, for apportioning PAH sources. Among which, DRs and PCA identified as the most widely employed method, but their accuracy for PAH source identification has received global criticism. Therefore, the review recommends compound-specific isotopic analysis (CSIA) and PMF as the best alternative methods to provide detailed qualitative and quantitative source analysis. The compound-specific isotopic signatures are not affected by environmental degradation and are considered promising for apportioning PAH sources. However, isotopic fractions of co-eluted compounds like polar PAHs and aliphatic hydrocarbons make the PAHs isotopic fractions interpretation difficult. The interference of unresolved complex mixtures is a limitation to the application of CSIA for PAH source apportionment. Hence, for CSIA to further support PAH source apportionment, fast and cost-effective purification techniques with no isotopic fractionation effects are highly desirable. The present review explains the concept of stable carbon isotopic analysis (SCIA) relevant to PAH source analysis, identifying the techniques suitable for sample extract purification. We demonstrate how the source apportioned PAHs can be applied in assessing the health risk of PAHs using the incremental lifetime cancer risk (ILCR) model, and in doing so, we identify the key factors that could undermine the accuracy of the ILCR and research gaps that need further investigation. (c) 2021 Elsevier B.V. All rights reserved.
资助项目	Ningbo Science and Technology Innovation 2025 Key Project[2020Z100] ; Ningbo Municipal Commonweal Key Program[2019C10033] ; Ningbo Municipal Commonweal Key Program[2019C10104] ; National Natural Science Foundation of China[41975831] ; National Natural Science Foundation of China[41625006] ; National Natural Science Foundation of China[41761144066] ; National Natural Science Foundation of China[41561144005] ; National Key Research and Development Program of China[2017YFC0212703] ; Provincial Key Laboratory Program by Zhejiang Provincial Department of Science and Technology[2020E10018]
WOS关键词	ACCELERATED SOLVENT-EXTRACTION ; MICROWAVE-ASSISTED EXTRACTION ; POSITIVE MATRIX FACTORIZATION ; PRESSURE CHEMICAL-IONIZATION ; AIRBORNE PARTICULATE MATTER ; CARBON-ISOTOPE RATIO ; SOURCE APPORTIONMENT ; MASS-SPECTROMETRY ; AMBIENT AIR ; SIZE DISTRIBUTION
WOS研究方向	Environmental Sciences & Ecology
语种	英语
出版者	ELSEVIER
WOS记录号	WOS:000677551200010
资助机构	Ningbo Science and Technology Innovation 2025 Key Project ; Ningbo Municipal Commonweal Key Program ; National Natural Science Foundation of China ; National Key Research and Development Program of China ; Provincial Key Laboratory Program by Zhejiang Provincial Department of Science and Technology
内容类型	期刊论文
源URL	[http://ir.igsnrr.ac.cn/handle/311030/164835]
专题	中国科学院地理科学与资源研究所
通讯作者	Guo, Qingjun; He, Jun
作者单位	1.Univ Nottingham Ningbo China, Key Lab Carbonaceous Wastes Proc & Proc Intensifi, Ningbo 315100, Peoples R China 2.Chinese Acad Sci, Inst Geog Sci & Nat Resources Res, Ctr Environm Remediat, Beijing 100101, Peoples R China 3.Univ Nottingham Ningbo China, Dept Chem & Environm Engn, 199 Taikang E Rd, Ningbo 315100, Peoples R China 4.Univ Birmingham, Sch Geog Earth & Environm Sci, Birmingham B15 2TT, W Midlands, England 5.South Cent Univ Nationalities, Coll Resources & Environm Sci, Wuhan 430074, Peoples R China 6.Supreme Peoples Procuratorate, Procuratoral Technol & Informat Res Ctr, Beijing 100144, Peoples R China 7.Univ Nottingham Ningbo China, Dept Geog Sci, 199 Taikang E Rd, Ningbo 315100, Peoples R China 8.China Univ Geosci, Sch Environm Studies, Dept Atmospher Sci, Wuhan 430074, Peoples R China 9.Univ Nottingham, Dept Chem & Environm Engn, Univ Pk, Nottingham NG7 2RD, England
推荐引用方式 GB/T 7714	Famiyeh, Lord,Chen, Ke,Xu, Jingsha,et al. A review on analysis methods, source identification, and cancer risk evaluation of atmospheric polycyclic aromatic hydrocarbons[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2021,789:18.
APA	Famiyeh, Lord.,Chen, Ke.,Xu, Jingsha.,Sun, Yong.,Guo, Qingjun.,...&He, Jun.(2021).A review on analysis methods, source identification, and cancer risk evaluation of atmospheric polycyclic aromatic hydrocarbons.SCIENCE OF THE TOTAL ENVIRONMENT,789,18.
MLA	Famiyeh, Lord,et al."A review on analysis methods, source identification, and cancer risk evaluation of atmospheric polycyclic aromatic hydrocarbons".SCIENCE OF THE TOTAL ENVIRONMENT 789(2021):18.