Biodegradation mechanism of typical fluoroquinolones in sewage-sludge composts

doi:10.5004/dwt.2021.27198

	Biodegradation mechanism of typical fluoroquinolones in sewage-sludge composts
	Zhang, Jun 2,3; Lu, Yulan 2,3; Yan, Qinying 2,3; Liu, Hongtao 1; Xi, Beidou 4; Wang, Dunqiu 2,3
刊名	DESALINATION AND WATER TREATMENT
	2021-06-01
卷号	225 页码:63-75
关键词	Sewage sludge Antibiotics Composting Biodegradation Microbial community
ISSN号	1944-3994
DOI	10.5004/dwt.2021.27198
通讯作者	Zhang, Jun(zjun@glut.edu.cn)
英文摘要	The biodegradation mechanism of fluoroquinolones (FQs) during composting is the key information to accurately assess and effectively control the environmental risk caused by FQs in sewage sludge. This study investigated the biodegradation of two FQs (norfloxacin [NOR] and ofloxacin [OFL]) using a series of sludge composts over a 56-d incubation period. Sludge composts were collected at the mesophilic, thermophilic, and curing phases from the matrix of a pilot-scale sewage sludge composter; spiked with NOR and OFL (each 5 mg/kg); and incubated at 35 (mesophilic), 55 (thermophilic), and 40 degrees C (curing). Compost samples were evaluated by determining FQ concentration, intermediate metabolites, enzymatic activity (laccase, manganese peroxidase, and lignin peroxidase), and bacterial and fungal communities. Results showed that NOR was likely to be predominantly biodegraded via the acetylation route and the routes for OFL in each phase varied, while the main metabolites from both NOR and OFL retained the FQ core structure related to the antibacterial activity. Only manganese peroxidase had a significant correlation with FQ residue during the mesophilic phase. Proteobacteria and Ascomycota were the dominant bacterial and fungal phyla in the incubated sludge compost, respectively, and Pseudomonas was the most involved bacterial genus for FQ biodegradation in the sludge composts with Exophiala, Dissoconium, Talaromyces as the fungal genera.
资助项目	National Natural Science Foundation of China[51868011] ; Department of Science and Technology of Guangxi Zhuang Autonomous Region[2018GXNSFGA281001] ; Department of Science and Technology of Guangxi Zhuang Autonomous Region[2016GXNSFAA380005] ; Special Fund for Guangxi Distinguished Experts
WOS关键词	ANTIBIOTIC-RESISTANCE GENES ; WASTE-WATER ; VETERINARY ANTIBIOTICS ; ANTIBACTERIAL ACTIVITY ; EFFICIENT REDUCTION ; TREATMENT PLANTS ; DEGRADATION ; FATE ; NORFLOXACIN ; REMOVAL
WOS研究方向	Engineering ; Water Resources
语种	英语
出版者	DESALINATION PUBL
WOS记录号	WOS:000672133600008
资助机构	National Natural Science Foundation of China ; Department of Science and Technology of Guangxi Zhuang Autonomous Region ; Special Fund for Guangxi Distinguished Experts
内容类型	期刊论文
源URL	[http://ir.igsnrr.ac.cn/handle/311030/163871]
专题	中国科学院地理科学与资源研究所
通讯作者	Zhang, Jun
作者单位	1.Chinese Acad Sci, Inst Geog Sci & Nat Resources Res, Beijing 100101, Peoples R China 2.Guilin Univ Technol, Guangxi Key Lab Environm Pollut Control Theory &, Guilin 541004, Peoples R China 3.Guilin Univ Technol, Collaborat Innovat Ctr Water Pollut Control & Wat, Guilin 541004, Peoples R China 4.Chinese Res Inst Environm Sci, State Key Lab Environm Criteria & Risk Assessment, Beijing 100012, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Jun,Lu, Yulan,Yan, Qinying,et al. Biodegradation mechanism of typical fluoroquinolones in sewage-sludge composts[J]. DESALINATION AND WATER TREATMENT,2021,225:63-75.
APA	Zhang, Jun,Lu, Yulan,Yan, Qinying,Liu, Hongtao,Xi, Beidou,&Wang, Dunqiu.(2021).Biodegradation mechanism of typical fluoroquinolones in sewage-sludge composts.DESALINATION AND WATER TREATMENT,225,63-75.
MLA	Zhang, Jun,et al."Biodegradation mechanism of typical fluoroquinolones in sewage-sludge composts".DESALINATION AND WATER TREATMENT 225(2021):63-75.