Perioperative change in neutrophil count predicts worse survival in esophageal squamous cell carcinoma

doi:10.2217/fon-2021-0371

	Perioperative change in neutrophil count predicts worse survival in esophageal squamous cell carcinoma
	Song, Qian 1,2; Wu, Junzhou 2,3; Wang, Sheng 1,2; Xu, Songxiao 1,2
刊名	FUTURE ONCOLOGY
	2021-08-25
关键词	esophageal squamous cell carcinoma neutrophil perioperative change prognosis survival
ISSN号	1479-6694
DOI	10.2217/fon-2021-0371
通讯作者	Xu, Songxiao(xusx@zjcc.org.cn)
英文摘要	Aims: This study aimed to investigate the relationship between perioperative change in neutrophil count and survival of patients with esophageal squamous cell carcinoma. Method: Neutrophil change (Nc) (where Nc = post-surgery neutrophil count - pre-surgery neutrophil count) was counted according to data within 1 week before surgery and 2 weeks after surgery. Patients were divided into two groups, Nc >= 2.60 and Nc <2.60, according to the median of Nc. Results: Multivariate analysis revealed that Nc >= 2.60 was an independent prognostic marker for overall survival. Subgroup analysis suggested that the overall survival of male patients, patients aged <= 60 years, patients without vessel invasion and patients without nerve infiltration was dramatically worse for those with Nc Conclusion: Perioperative change in neutrophil count predicts worse survival in esophageal squamous cell carcinoma after surgery.
资助项目	National Natural Science Foundation of China[81602615] ; Zhejiang Youth Talents Project[2019RC026] ; General research program of Health Department of Zhejiang Province[2020KY480] ; Natural Science Foundation of Zhejiang Province[LQ21H200001]
WOS关键词	CIRCULATING TUMOR-CELLS ; PROGNOSTIC-FACTOR ; LYMPHOCYTE RATIO ; T-CELLS ; PROMOTE ; CANCER ; MICROENVIRONMENT ; METASTASIS ; EXPRESSION ; RISK
WOS研究方向	Oncology
语种	英语
出版者	FUTURE MEDICINE LTD
WOS记录号	WOS:000688122200001
资助机构	National Natural Science Foundation of China ; Zhejiang Youth Talents Project ; General research program of Health Department of Zhejiang Province ; Natural Science Foundation of Zhejiang Province
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/125179]
专题	中国科学院合肥物质科学研究院
通讯作者	Xu, Songxiao
作者单位	1.Univ Chinese Acad Sci, Canc Hosp, Zhejiang Canc Hosp, Dept Clin Lab, Hangzhou 310022, Zhejiang, Peoples R China 2.Chinese Acad Sci, Inst Basic Med & Canc IBMC, Hangzhou 310022, Zhejiang, Peoples R China 3.Univ Chinese Acad Sci, Canc Hosp, Canc Res Inst, Zhejiang Canc Hosp, Hangzhou 310022, Zhejiang, Peoples R China
推荐引用方式 GB/T 7714	Song, Qian,Wu, Junzhou,Wang, Sheng,et al. Perioperative change in neutrophil count predicts worse survival in esophageal squamous cell carcinoma[J]. FUTURE ONCOLOGY,2021.
APA	Song, Qian,Wu, Junzhou,Wang, Sheng,&Xu, Songxiao.(2021).Perioperative change in neutrophil count predicts worse survival in esophageal squamous cell carcinoma.FUTURE ONCOLOGY.
MLA	Song, Qian,et al."Perioperative change in neutrophil count predicts worse survival in esophageal squamous cell carcinoma".FUTURE ONCOLOGY (2021).