Bench-stable imine surrogates for the one-pot and catalytic asymmetric synthesis of alpha-amino esters/ketones

doi:10.1039/d0cc06055k

	Bench-stable imine surrogates for the one-pot and catalytic asymmetric synthesis of alpha-amino esters/ketones
	Xu, Huacheng 1; Nazli, Adila 1; Zou, Cheng 1; Wang, Zhi-Peng 2; He, Yun 1
刊名	CHEMICAL COMMUNICATIONS
	2020-11-25
卷号	56 期号:91 页码:14243-14246
ISSN号	1359-7345
DOI	10.1039/d0cc06055k
通讯作者	Wang, Zhi-Peng(wangzhipeng@cigit.ac.cn) ; He, Yun(yun.he@cqu.edu.cn)
英文摘要	N,O-Bis(tert-butoxycarbonyl)hydroxylamines are readily accessible as imine surrogates, which are bench stable and could quantitatively generate the corresponding imines for in situ applications. An unpresented catalytic asymmetric method for the synthesis of alpha-amino esters and ketones from novel imine surrogates, N,O-bis(tert-butoxycarbonyl)hydroxylamines, as well as its preliminary mechanistic studies are reported. A variety of optically enriched products were obtained in excellent yields and enantioselectivities (up to 99% yield and >99% ee).
资助项目	Ministry of Science and Technology of China[2019ZX09301-164] ; Natural Science Foundation of Chongqing, China[cstc2019jcyj-zdxmX0021]
WOS研究方向	Chemistry
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000590124000020
内容类型	期刊论文
源URL	[http://119.78.100.138/handle/2HOD01W0/12348]
专题	中国科学院重庆绿色智能技术研究院
通讯作者	Wang, Zhi-Peng; He, Yun
作者单位	1.Chongqing Univ, Sch Pharmaceut Sci, Chongqing Key Lab Nat Prod Synth & Drug Res, Chongqing 401331, Peoples R China 2.Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Chongqing 400714, Peoples R China
推荐引用方式 GB/T 7714	Xu, Huacheng,Nazli, Adila,Zou, Cheng,et al. Bench-stable imine surrogates for the one-pot and catalytic asymmetric synthesis of alpha-amino esters/ketones[J]. CHEMICAL COMMUNICATIONS,2020,56(91):14243-14246.
APA	Xu, Huacheng,Nazli, Adila,Zou, Cheng,Wang, Zhi-Peng,&He, Yun.(2020).Bench-stable imine surrogates for the one-pot and catalytic asymmetric synthesis of alpha-amino esters/ketones.CHEMICAL COMMUNICATIONS,56(91),14243-14246.
MLA	Xu, Huacheng,et al."Bench-stable imine surrogates for the one-pot and catalytic asymmetric synthesis of alpha-amino esters/ketones".CHEMICAL COMMUNICATIONS 56.91(2020):14243-14246.