Chemical components of Hyssopus cuspidatus Boriss.: isolation and identification, characterization by HPLC-DAD-ESI-HRMS/MS, antioxidant activity and antimicrobial activity

doi:10.1080/14786419.2018.1488710

CORC > 新疆理化技术研究所 > 中国科学院新疆理化技术研究所 > 省部共建新疆特有药用资源利用重点实验室

	Chemical components of Hyssopus cuspidatus Boriss.: isolation and identification, characterization by HPLC-DAD-ESI-HRMS/MS, antioxidant activity and antimicrobial activity
	Shomirzoeva, O (Shomirzoeva, Omina)[ 1,2,3 ]; Li, J (Li, Jun)[ 1,2 ]; Numonov, S (Numonov, Sodik)[ 1,2 ]; Atolikshoeva, S (Atolikshoeva, Sunbula)[ 1,2,3 ]; Aisa, HA (Aisa, Haji Akber)[ 1,2 ]
刊名	NATURAL PRODUCT RESEARCH
	2020
卷号	34 期号:4 页码:534-540
关键词	Hyssopus cuspidatus Boriss chemical composition isolation and identification HPLC-DAD-ESI-HRMS MS antioxidant antibacterial
ISSN号	1478-6419
DOI	10.1080/14786419.2018.1488710
英文摘要	Eighteen compounds were isolated from the ethyl acetate fraction of the aerial part of Hyssopus cuspidatus. Their structures were established by analysis of mass and NMR data, as well as comparison with previous published data in the literatures. Among them, ten compounds were found from the Hyssopus genus for the first time, and one compound was isolated from H. cuspidatus for the first time. HPLC-DAD-ESI-HRMS/MS investigations was applied to further obtain the phenolic profiling of the ethyl acetate fraction, and nine derivatives of caffeic acid and ferulic or isoferulic acid were identified. Antioxidant activity against DPPH free radical and antibacterial activity against Candida albicans, Escherichia coli and Staphylococcus aureus were evaluated. The ethyl acetate fraction exhibited weak antioxidant activity and moderate antibacterial activity. The isolated compounds showed weak to potent antioxidant and antibacterial activity. To the best of our knowledge, this is the first report on the antioxidant and antibacterial activity of H. cuspidatus.
WOS记录号	WOS:000534089300013
内容类型	期刊论文
源URL	[http://ir.xjipc.cas.cn/handle/365002/7683]
专题	新疆理化技术研究所_省部共建新疆特有药用资源利用重点实验室
通讯作者	Aisa, HA (Aisa, Haji Akber)[ 1,2 ]
作者单位	1.Univ Chinese Acad Sci, Beijing, Peoples R China 2.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, State Key Lab Basis Xinjiang Indigenous Med Plant, Urumqi, Peoples R China 3.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Chem Arid Zone, Urumqi, Peoples R China
推荐引用方式 GB/T 7714	Shomirzoeva, O ,Li, J ,Numonov, S ,et al. Chemical components of Hyssopus cuspidatus Boriss.: isolation and identification, characterization by HPLC-DAD-ESI-HRMS/MS, antioxidant activity and antimicrobial activity[J]. NATURAL PRODUCT RESEARCH,2020,34(4):534-540.
APA	Shomirzoeva, O ,Li, J ,Numonov, S ,Atolikshoeva, S ,&Aisa, HA .(2020).Chemical components of Hyssopus cuspidatus Boriss.: isolation and identification, characterization by HPLC-DAD-ESI-HRMS/MS, antioxidant activity and antimicrobial activity.NATURAL PRODUCT RESEARCH,34(4),534-540.
MLA	Shomirzoeva, O ,et al."Chemical components of Hyssopus cuspidatus Boriss.: isolation and identification, characterization by HPLC-DAD-ESI-HRMS/MS, antioxidant activity and antimicrobial activity".NATURAL PRODUCT RESEARCH 34.4(2020):534-540.