Degradation of Laminaria japonica fucoidan by hydrogen peroxide and antioxidant activities of the degradation products of different molecular weights

	Degradation of Laminaria japonica fucoidan by hydrogen peroxide and antioxidant activities of the degradation products of different molecular weights
	Hou, Yun 1,2; Wang, Jing1 ; Jin, Weihua 1,2; Zhang, Hong 1; Zhang, Quanbin 1
刊名	CARBOHYDRATE POLYMERS
	2012-01-04
卷号	87 期号:1 页码:153-159
关键词	Fucoidan Degradation Hydrogen peroxide Antioxidant
ISSN号	0144-8617
通讯作者	Zhang, QB (reprint author), Chinese Acad Sci, Inst Oceanol, 7 Naihai Rd, Qingdao 266071, Peoples R China.
英文摘要	Conditions of fucoidan degradation by hydrogen peroxide and the antioxidant activities of fucoidans with different molecular weights (Mws) were studied. Fucoidan degradation was monitored by gel permeation chromatography (GPC). Results showed that higher reaction temperature, hydrogen peroxide concentration and reaction time were the main factors that determined the decrease in Mw. There were no significant chemical changes in the backbones of the fucoidans treated with hydrogen peroxide, and the sulphate group contents barely change as compared to the raw polysaccharide. The antioxidant activities of seven fucoidans with different Mws (1.0 kDa, 3.8 kDa, 8.3 kDa, 13.2 kDa, 35.5 kDa, 64.3 kDa, 144.5 kDa) were assessed. The results showed that the relationship between Mws of fucoidans and their antioxidant activities is not simply linear. The samples with Mws of 3.8 kDa, 1.0 kDa and >8.3 kDa have better hydroxyl radical scavenging activity, reducing power and superoxide anion scavenging activity, respectively. (C) 2011 Elsevier Ltd. All rights reserved.
学科主题	Chemistry, Applied ; Chemistry, Organic ; Polymer Science
收录类别	SCI
原文出处	10.1016/j.carbpol.2011.07.031
语种	英语
WOS记录号	WOS:000297389000021
公开日期	2013-09-24
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/12217]
专题	海洋研究所_海洋生物技术研发中心
作者单位	1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Hou, Yun,Wang, Jing,Jin, Weihua,et al. Degradation of Laminaria japonica fucoidan by hydrogen peroxide and antioxidant activities of the degradation products of different molecular weights[J]. CARBOHYDRATE POLYMERS,2012,87(1):153-159.
APA	Hou, Yun,Wang, Jing,Jin, Weihua,Zhang, Hong,&Zhang, Quanbin.(2012).Degradation of Laminaria japonica fucoidan by hydrogen peroxide and antioxidant activities of the degradation products of different molecular weights.CARBOHYDRATE POLYMERS,87(1),153-159.
MLA	Hou, Yun,et al."Degradation of Laminaria japonica fucoidan by hydrogen peroxide and antioxidant activities of the degradation products of different molecular weights".CARBOHYDRATE POLYMERS 87.1(2012):153-159.