Recent advances in chemical analysis of licorice (Gan-Cao)

doi:10.1016/j.fitote.2020.104803

	Recent advances in chemical analysis of licorice (Gan-Cao)
	Cheng, Mengzhen 1,2; Zhang, Jianqing 2; Yang, Lin 2; Shen, Shijie 2; Li, Ping 2; Yao, Shuai 2; Qu, Hua 2; Li, Jiayuan 2; Yao, Changliang 2; Wei, Wenlong 2
刊名	FITOTERAPIA
	2021-03-01
卷号	149 页码:12
关键词	Glycyrrhiza uralensis Glycyrrhiza glabra Glycyrrhiza inflata Gan-Cao Qualitative and quantitative analysis Biological sample
ISSN号	0367-326X
DOI	10.1016/j.fitote.2020.104803
通讯作者	Guo, De-an(daguo@simm.ac.cn)
英文摘要	Gan-Cao, or licorice, the dried roots and rhizomes of Glycyrrhiza uralensis, G.glabra, and ainflata, has received considerable interest due to its extensive application in traditional Chinese medicine (TCM) prescriptions (60% approximately), clinical therapy, and as food additives world-wide. Chemical analysis is an important approach to understand the active pharmaceutical components in licorice and its prescriptions, as well as to develop novel methodologies for their quality assessment and control. This comprehensive review describes the advances in the chemical analysis, including sample preparation methods, qualitative and quantitative analysis and biological specimen analysis, based on 113 references for the recent years. Newly established methods are summarized, such as high performance thin layer chromatography (HPTLC), high performance liquid chromatography (HPLC), liquid chromatography tandem mass spectrometry (LC-MS), capillary electrophoresis (CE) and near infrared spectroscopy (NIR), which allows the identification, authentication, and simultaneous detection of multiple compounds in licorice with higher throughput and sensitivity. It is anticipated that this review could provide imperative information for improving the existing quality evaluation methods of licorice and afford scientific basis for further researches on the pharmacodynamic substances of licorice.
资助项目	National Key R&D Program of China[2019YFC1711000] ; National Natural Science Foundation of China[82003940]
WOS关键词	HERBAL MEDICINE ; STRATEGY
WOS研究方向	Pharmacology & Pharmacy
语种	英语
出版者	ELSEVIER
WOS记录号	WOS:000619206900004
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/295706]
专题	中国科学院上海药物研究所
通讯作者	Guo, De-an
作者单位	1.Nanjing Univ Chinese Med, Sch Chinese Mat Med, Nanjing 210023, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, Haike Rd 501, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Cheng, Mengzhen,Zhang, Jianqing,Yang, Lin,et al. Recent advances in chemical analysis of licorice (Gan-Cao)[J]. FITOTERAPIA,2021,149:12.
APA	Cheng, Mengzhen.,Zhang, Jianqing.,Yang, Lin.,Shen, Shijie.,Li, Ping.,...&Guo, De-an.(2021).Recent advances in chemical analysis of licorice (Gan-Cao).FITOTERAPIA,149,12.
MLA	Cheng, Mengzhen,et al."Recent advances in chemical analysis of licorice (Gan-Cao)".FITOTERAPIA 149(2021):12.