A review on analytical methods for natural berberine alkaloids

doi:10.1002/jssc.201800952

	A review on analytical methods for natural berberine alkaloids
	Wang, Jiahui 1; Jiang, Yanyan 2; Wang, Bing 3,4; Zhang, Ning 1
刊名	JOURNAL OF SEPARATION SCIENCE
	2019-05-01
卷号	42 期号:9 页码:1794-1815
关键词	berberine alkaloids gas chromatography liquid chromatography mass spectrometry thin-layer chromatography
ISSN号	1615-9306
DOI	10.1002/jssc.201800952
通讯作者	Wang, Bing(bwang@simm.ac.cn) ; Zhang, Ning(ningzh18@126.com)
英文摘要	Berberine alkaloids, a group of protoberberine alkaloids under the classification of isoquinoline alkaloids, include berberine, coptisine, palmatine, columbamine, dehydrocorydaline, jatrorrhizine, and epiberberine from natural sources. Studies have shown that berberine alkaloids have various pharmacological functions, such as antibacterial, antiviral, blood pressure-lowering, hypoglycaemic, antiarrhythmia, and anticancer effects. Therefore, it is worthwhile to develop analytical methods to investigate the pharmacokinetics and activity mechanisms of berberine alkaloids and to study berberine alkaloids more comprehensively. Current analytical methods for berberine alkaloids include liquid chromatography, thin-layer chromatography, ultraviolet spectroscopy, capillary electrophoresis, and gas chromatography. The most widely used detection method is mass spectrometry. In order to provide a systematic and comprehensive summary and to serve as a reference for the future pharmacokinetics studies and analysis of berberine alkaloids, analytical methods for natural berberine alkaloids that have been used in the past ten years are reviewed here.
资助项目	Shanghai Committee of Science and Technology[17401902300]
WOS关键词	PERFORMANCE LIQUID-CHROMATOGRAPHY ; TANDEM MASS-SPECTROMETRY ; TRADITIONAL CHINESE MEDICINE ; PROCESSED RHIZOMA-COPTIDIS ; RAT PLASMA APPLICATION ; UPLC-MS/MS METHOD ; DRUG PHARMACOKINETIC INTERACTION ; MAJOR BIOACTIVE COMPONENTS ; TYPE-2 DIABETIC-RATS ; SI-WU DECOCTION
WOS研究方向	Chemistry
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000471322300004
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/289443]
专题	中国科学院上海药物研究所
通讯作者	Wang, Bing; Zhang, Ning
作者单位	1.Shanghai Univ Tradit Chinese Med, Expt Ctr Sci & Technol, Shanghai, Peoples R China 2.Fudan Univ, Key Lab Smart Drug Delivery, Minist Educ & PLA, Dept Pharmaceut,Sch Pharm, Shanghai, Peoples R China 3.Shanghai Univ Tradit Chinese Med, Sch Pharm, 1200 Cai lun Rd, Shanghai 201203, Peoples R China 4.Chinese Acad Sci, Shanghai Inst Materia Med, Shanghai, Peoples R China
推荐引用方式 GB/T 7714	Wang, Jiahui,Jiang, Yanyan,Wang, Bing,et al. A review on analytical methods for natural berberine alkaloids[J]. JOURNAL OF SEPARATION SCIENCE,2019,42(9):1794-1815.
APA	Wang, Jiahui,Jiang, Yanyan,Wang, Bing,&Zhang, Ning.(2019).A review on analytical methods for natural berberine alkaloids.JOURNAL OF SEPARATION SCIENCE,42(9),1794-1815.
MLA	Wang, Jiahui,et al."A review on analytical methods for natural berberine alkaloids".JOURNAL OF SEPARATION SCIENCE 42.9(2019):1794-1815.