Copper-mediated O-arylation of lactols with aryl boronic acids

doi:10.1016/j.cclet.2019.06.014

	Copper-mediated O-arylation of lactols with aryl boronic acids
	Sui, Jing-Jing 1,2; Xiong, De-Cai 1,3; Ye, Xin-Shan 1,2
刊名	CHINESE CHEMICAL LETTERS
	2019-08-01
卷号	30 期号:8 页码:1533-1537
关键词	Phenolic glycoside O-Arylation Lactol Aryl boronic acid
ISSN号	1001-8417
DOI	10.1016/j.cclet.2019.06.014
通讯作者	Xiong, De-Cai(decai@bjmu.edu.cn) ; Ye, Xin-Shan(xinshan@bjmu.edu.cn)
英文摘要	An efficient and novel methodology to access phenolic glycosides has been established by using copper-mediated coupling reaction of aryl boronic acids with hemiacetals. The reaction takes place normally in the presence of Cu(OAc)(2) (1.0 equiv.) and pyridine (2.0 equiv.) at 40 degrees C. This protocol distinguishes itself by wide substrate scope, operational simplicity and giving rise to a myriad of phenolic glycosides in good to excellent yields. (C) 2019 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
资助项目	National Key R&D Program of China[2018YFA0507602] ; National Natural Science Foundation of China[21572012] ; National Natural Science Foundation of China[21772006] ; State Key Laboratory of Drug Research[SIMM1803KF-02]
WOS关键词	FACILE SYNTHESIS ; GLYCOSYLATION ; DERIVATIVES ; MITHRAMYCIN ; GLYCALS
WOS研究方向	Chemistry
语种	英语
出版者	ELSEVIER SCIENCE INC
WOS记录号	WOS:000482249800016
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/288733]
专题	中国科学院上海药物研究所
通讯作者	Xiong, De-Cai; Ye, Xin-Shan
作者单位	1.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China 2.Jiangxi Normal Univ, Natl Res Ctr Carbohydrate Synth, Nanchang 330022, Jiangxi, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Sui, Jing-Jing,Xiong, De-Cai,Ye, Xin-Shan. Copper-mediated O-arylation of lactols with aryl boronic acids[J]. CHINESE CHEMICAL LETTERS,2019,30(8):1533-1537.
APA	Sui, Jing-Jing,Xiong, De-Cai,&Ye, Xin-Shan.(2019).Copper-mediated O-arylation of lactols with aryl boronic acids.CHINESE CHEMICAL LETTERS,30(8),1533-1537.
MLA	Sui, Jing-Jing,et al."Copper-mediated O-arylation of lactols with aryl boronic acids".CHINESE CHEMICAL LETTERS 30.8(2019):1533-1537.