Recent progress in drug delivery

doi:10.1016/j.apsb.2019.08.003

	Recent progress in drug delivery
	Li, Chong 2; Wang, Jiancheng 3; Wang, Yiguang 3; Gao, Huile 4; Wei, Gang 5; Huang, Yongzhuo 1; Yu, Haijun 1; Gan, Yong 1; Wang, Yongjun 6; Mei, Lin 7
刊名	ACTA PHARMACEUTICA SINICA B
	2019-11-01
卷号	9 期号:6 页码:1145-1162
关键词	Pharmaceutics Drug delivery system Basic research Application Delivery strategy
ISSN号	2211-3835
DOI	10.1016/j.apsb.2019.08.003
通讯作者	Wang, Jiancheng(wang-jc@bjmu.edu.cn)
英文摘要	Drug delivery systems (DDS) are defined as methods by which drugs are delivered to desired tissues, organs, cells and subcellular organs for drug release and absorption through a variety of drug carriers. Its usual purpose to improve the pharmacological activities of therapeutic drugs and to overcome problems such as limited solubility, drug aggregation, low bioavailability, poor biodistribution, lack of selectivity, or to reduce the side effects of therapeutic drugs. During 2015-2018, significant progress in the research on drug delivery systems has been achieved along with advances in related fields, such as pharmaceutical sciences, material sciences and biomedical sciences. This review provides a concise overview of current progress in this research area through its focus on the delivery strategies, construction techniques and specific examples. It is a valuable reference for pharmaceutical scientists who want to learn more about the design of drug delivery systems. (C) 2019 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V.
资助项目	National Natural Science Foundation of China[81773650] ; National Natural Science Foundation of China[81690264] ; National Natural Science Foundation of China[81673376] ; Drug Innovation Major Project of China[2018ZX09721003-004]
WOS关键词	MESOPOROUS SILICA NANOPARTICLES ; IN-VIVO PHARMACOKINETICS ; ORAL DELIVERY ; SIRNA DELIVERY ; TARGETED NANOASSEMBLIES ; CANCER-IMMUNOTHERAPY ; COMBINATION THERAPY ; SENSITIVE VESICLES ; MEMBRANE-RECEPTORS ; TUMOR PENETRATION
WOS研究方向	Pharmacology & Pharmacy
语种	英语
出版者	INST MATERIA MEDICA, CHINESE ACAD MEDICAL SCIENCES
WOS记录号	WOS:000500912700004
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/282117]
专题	中国科学院上海药物研究所
通讯作者	Wang, Jiancheng
作者单位	1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China 2.Southwest Univ, Coll Pharmaceut Sci, Chongqing 400715, Peoples R China 3.Peking Univ, Sch Pharmaceut Sci, Beijing Key Lab Mol Pharmaceut & New Drug Deliver, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China 4.Sichuan Univ, West China Sch Pharm, Key Lab Drug Targeting & Drug Delivery Syst, Chengdu 610041, Sichuan, Peoples R China 5.Fudan Univ, Key Lab Smart Drug Delivery, Minist Educ, Shanghai 201203, Peoples R China 6.Shenyang Pharmaceut Univ, Sch Pharm, Shenyang 110016, Liaoning, Peoples R China 7.Sun Yat Sen Univ, Sch Pharmaceut Sci Shenzhen, Guangzhou 510275, Guangdong, Peoples R China 8.Soochow Univ, Sch Radiat Med & Protect, Suzhou 215123, Peoples R China 9.Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou 510006, Guangdong, Peoples R China 10.Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Pharm, Wuhan 430030, Hubei, Peoples R China
推荐引用方式 GB/T 7714	Li, Chong,Wang, Jiancheng,Wang, Yiguang,et al. Recent progress in drug delivery[J]. ACTA PHARMACEUTICA SINICA B,2019,9(6):1145-1162.
APA	Li, Chong.,Wang, Jiancheng.,Wang, Yiguang.,Gao, Huile.,Wei, Gang.,...&Jin, Yiguang.(2019).Recent progress in drug delivery.ACTA PHARMACEUTICA SINICA B,9(6),1145-1162.
MLA	Li, Chong,et al."Recent progress in drug delivery".ACTA PHARMACEUTICA SINICA B 9.6(2019):1145-1162.