Celamonols A-D, four triterpenoid and catechin conjugates with immunosuppressive activities from the stems of Celastrus monospermus

doi:10.1039/c9qo00974d

	Celamonols A-D, four triterpenoid and catechin conjugates with immunosuppressive activities from the stems of Celastrus monospermus
	Qin, Jun-Jun 2,3; Fu, Yi-Fan 2,3; Chen, Xi 1,4; Liu, Yu-Ting 3,4; Zhao, Ji-Hui 3,4; Zuo, Jian-Ping 1,4; Li, Yi-Ming 1; Zhu, Wei-Liang 4; Zhao, Wei-Min 2
刊名	ORGANIC CHEMISTRY FRONTIERS
	2019-11-21
卷号	6 期号:22 页码:3786-3792
ISSN号	2052-4129
DOI	10.1039/c9qo00974d
通讯作者	Li, Yi-Ming() ; Zhu, Wei-Liang() ; Zhao, Wei-Min()
英文摘要	Celamonols A-D (1-4), featuring an unusual pattern of conjunction between a 24,29-dinorfriedelane-type triterpenoid and a catechin, were isolated from the stems of Celastrus monospermus. Their structures were elucidated by extensive spectroscopic analyses, modified Mosher's method, and ECD calculations. Compounds 1 and 4 exhibited moderate activities against the proliferation of B lymphocytes with IC50 values of 1.46 and 1.35 mu M, respectively.
资助项目	National Natural Science Foundation of China[81473113] ; State Key Laboratory of Drug Reasearch[SIMM1601KF-03]
WOS关键词	CHEMICAL-CONSTITUENTS ; SESQUITERPENOIDS ; ESTERS ; LEAVES
WOS研究方向	Chemistry
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000494737700011
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/281842]
专题	中国科学院上海药物研究所
通讯作者	Li, Yi-Ming; Zhu, Wei-Liang; Zhao, Wei-Min
作者单位	1.Shanghai Univ Tradit Chinese Med, 1200 Cailun Rd, Shanghai 201203, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, Dept Nat Prod Chem, Shanghai 201203, Peoples R China 3.Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Qin, Jun-Jun,Fu, Yi-Fan,Chen, Xi,et al. Celamonols A-D, four triterpenoid and catechin conjugates with immunosuppressive activities from the stems of Celastrus monospermus[J]. ORGANIC CHEMISTRY FRONTIERS,2019,6(22):3786-3792.
APA	Qin, Jun-Jun.,Fu, Yi-Fan.,Chen, Xi.,Liu, Yu-Ting.,Zhao, Ji-Hui.,...&Zhao, Wei-Min.(2019).Celamonols A-D, four triterpenoid and catechin conjugates with immunosuppressive activities from the stems of Celastrus monospermus.ORGANIC CHEMISTRY FRONTIERS,6(22),3786-3792.
MLA	Qin, Jun-Jun,et al."Celamonols A-D, four triterpenoid and catechin conjugates with immunosuppressive activities from the stems of Celastrus monospermus".ORGANIC CHEMISTRY FRONTIERS 6.22(2019):3786-3792.