Ir(iii)-Catalyzed direct C-H functionalization of N-phenylacetamide with alpha-diazo quinones: a novel strategy for producing 2-hydroxy-2 '-amino-1,2 '-biaryl scaffolds

doi:10.1039/c9cc08297b

	Ir(iii)-Catalyzed direct C-H functionalization of N-phenylacetamide with alpha-diazo quinones: a novel strategy for producing 2-hydroxy-2 '-amino-1,2 '-biaryl scaffolds
	Li, Xingjun 1,2,3,4; Wang, Jiang 3,4; Xie, Xiong 3,4; Dai, Wenhao 1,2,3,4; Han, Xu 3,4; Chen, Kaixian 1,2,3,4,5; Liu, Hong 1,2,3,4,5
刊名	CHEMICAL COMMUNICATIONS
	2020-03-21
卷号	56 期号:23 页码:3441-3444
ISSN号	1359-7345
DOI	10.1039/c9cc08297b
通讯作者	Chen, Kaixian() ; Liu, Hong()
英文摘要	alpha-Diazo quinones were applied in an Ir(iii)-catalyzed direct C-H functionalization assisted by N-phenylacetamide for the construction of highly functionalized 2-hydroxy-2 '-amino-1,1 '-biaryl scaffolds in good to excellent yields. This strategy features operational simplicity, atom- and step-economy and high efficiency.
资助项目	National Natural Science Foundation of China[21632008] ; National Natural Science Foundation of China[21672231] ; National Natural Science Foundation of China[21877118] ; National Natural Science Foundation of China[81620108027] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDA12040107] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDA12040201]
WOS关键词	KETENE DISILYL ACETALS ; RH(III)-CATALYZED SYNTHESIS ; LIGANDS ; DERIVATIVES ; CYCLIZATION ; INHIBITORS ; ARYLATION ; INDOLES ; ACCESS ; OXIDES
WOS研究方向	Chemistry
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000521320900017
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/280936]
专题	中国科学院上海药物研究所
通讯作者	Chen, Kaixian; Liu, Hong
作者单位	1.China Pharmaceut Univ, State Key Lab Nat Med, 24 Tong Jia Xiang, Nanjing 210009, Jiangsu, Peoples R China 2.China Pharmaceut Univ, Dept Med Chem, 24 Tong Jia Xiang, Nanjing 210009, Jiangsu, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zu Chong Zhi Rd, Shanghai 201203, Peoples R China 4.Chinese Acad Sci, Shanghai Inst Mat Med, Key Lab Receptor Res, 555 Zu Chong Zhi Rd, Shanghai 201203, Peoples R China 5.Pilot Natl Lab Marine Sci & Technol Qingdao, Open Studio Druggabil Res Marine Nat Prod, 1 Wenhai Rd, Qingdao 266237, Peoples R China
推荐引用方式 GB/T 7714	Li, Xingjun,Wang, Jiang,Xie, Xiong,et al. Ir(iii)-Catalyzed direct C-H functionalization of N-phenylacetamide with alpha-diazo quinones: a novel strategy for producing 2-hydroxy-2 '-amino-1,2 '-biaryl scaffolds[J]. CHEMICAL COMMUNICATIONS,2020,56(23):3441-3444.
APA	Li, Xingjun.,Wang, Jiang.,Xie, Xiong.,Dai, Wenhao.,Han, Xu.,...&Liu, Hong.(2020).Ir(iii)-Catalyzed direct C-H functionalization of N-phenylacetamide with alpha-diazo quinones: a novel strategy for producing 2-hydroxy-2 '-amino-1,2 '-biaryl scaffolds.CHEMICAL COMMUNICATIONS,56(23),3441-3444.
MLA	Li, Xingjun,et al."Ir(iii)-Catalyzed direct C-H functionalization of N-phenylacetamide with alpha-diazo quinones: a novel strategy for producing 2-hydroxy-2 '-amino-1,2 '-biaryl scaffolds".CHEMICAL COMMUNICATIONS 56.23(2020):3441-3444.