Effect of Gradient Nanostructured Ti on Behaviours of MG63 Cells In Vitro

doi:10.1155/2020/9480537

CORC > 金属研究所 > 中国科学院金属研究所

	Effect of Gradient Nanostructured Ti on Behaviours of MG63 Cells In Vitro
	Luo, Xue 4; Liang, Chen 1; Li, Ning 3; Zhu, Yuhe 4; Cao, Nanjue 2; Wang, Jin 4; Liu, Keda 4; Zhao, Hongwei 3; Wang, Zhenbo 1; Wang, Wei 4
刊名	JOURNAL OF NANOMATERIALS
	2020-06-05
卷号	2020 页码:11
ISSN号	1687-4110
DOI	10.1155/2020/9480537
通讯作者	Zhao, Hongwei(13931386052@163.com) ; Wang, Zhenbo(zbwang@imr.ac.cn) ; Wang, Wei(wwang75@cmu.edu.cn)
英文摘要	Titanium (Ti) is widely used in oral implants. However, there is still a challenge to promote the osseointegration of bone tissue on the surface of Ti. To solve this problem, we prepared novel gradient nanostructured (GNS) Ti and studied the effect of GNS on the adhesion, proliferation, and apoptosis of MG63 cellsin vitro. The results demonstrated that the GNS Ti promoted the adhesion effect and proliferation of MG63 cells better than the annealed Ti, while the ability of GNS Ti to inhibit cell apoptosis was better than that of the annealed Ti, the preliminary mechanism of which indicated by this study might be the enhanced mineralization capacity, protein adsorption ability, and hydrophilicity of the GNS Ti due to its specific nanostructure which improved the cell behaviours. The results in this study provide the theoretical and experimental foundations for the applications of GNS Ti in dental implants and joint replacements.
资助项目	National Natural Science Foundation of China[81970980] ; Liaoning Provincial Key Research Plan Guidance Project[2018225078] ; Liaoning Provincial Natural Science Foundation Guidance Project[2019-ZD-0749] ; Liaoning Province, Colleges and Universities Basic Research Project[LFWK201717] ; Central Government of Liaoning Province to Guide Local Science and Technology Development Project[2017108001] ; Shenyang Major Scientific and Technological Innovation Research and Development Plan[19-112-4-027] ; Second Batch of Medical Education Scientific Research Projects of the 13th Five-Year Plan of China Medical University[YDJK2018017]
WOS研究方向	Science & Technology - Other Topics ; Materials Science
语种	英语
出版者	HINDAWI LTD
WOS记录号	WOS:000548802600001
资助机构	National Natural Science Foundation of China ; Liaoning Provincial Key Research Plan Guidance Project ; Liaoning Provincial Natural Science Foundation Guidance Project ; Liaoning Province, Colleges and Universities Basic Research Project ; Central Government of Liaoning Province to Guide Local Science and Technology Development Project ; Shenyang Major Scientific and Technological Innovation Research and Development Plan ; Second Batch of Medical Education Scientific Research Projects of the 13th Five-Year Plan of China Medical University
内容类型	期刊论文
源URL	[http://ir.imr.ac.cn/handle/321006/139823]
专题	金属研究所_中国科学院金属研究所
通讯作者	Zhao, Hongwei; Wang, Zhenbo; Wang, Wei
作者单位	1.Chinese Acad Sci, Shenyang Natl Lab Mat Sci, Inst Met Res, Shenyang 110016, Peoples R China 2.Zhejiang Univ, Affiliated Hosp 4, Sch Med, Yiwu 322000, Peoples R China 3.Fourth Cent Hosp Baoding City, Dept Orthoped, Baoding 072350, Peoples R China 4.China Med Univ, Sch & Hosp Stomatol, Liaoning Prov Key Lab Oral Dis, Shenyang 110001, Peoples R China
推荐引用方式 GB/T 7714	Luo, Xue,Liang, Chen,Li, Ning,et al. Effect of Gradient Nanostructured Ti on Behaviours of MG63 Cells In Vitro[J]. JOURNAL OF NANOMATERIALS,2020,2020:11.
APA	Luo, Xue.,Liang, Chen.,Li, Ning.,Zhu, Yuhe.,Cao, Nanjue.,...&Wang, Wei.(2020).Effect of Gradient Nanostructured Ti on Behaviours of MG63 Cells In Vitro.JOURNAL OF NANOMATERIALS,2020,11.
MLA	Luo, Xue,et al."Effect of Gradient Nanostructured Ti on Behaviours of MG63 Cells In Vitro".JOURNAL OF NANOMATERIALS 2020(2020):11.