Effect of copper-doped titanium nitride coating on angiogenesis

doi:10.1016/j.matlet.2020.127634

CORC > 金属研究所 > 中国科学院金属研究所

	Effect of copper-doped titanium nitride coating on angiogenesis
	Liu, Hui 1,2; Zhang, Xiyue 1,2; Jin, Shujing 3; Zhao, Yanhui 1; Ren, Ling 1; Yang, Ke 1
刊名	MATERIALS LETTERS
	2020-06-15
卷号	269 页码:4
关键词	Biomaterials Coating Angiogenesis Human umbilical vein endothelial cells
ISSN号	0167-577X
DOI	10.1016/j.matlet.2020.127634
通讯作者	Zhao, Yanhui(yhzhao@imr.ac.cn) ; Ren, Ling(lren@imr.ac.cn)
英文摘要	This work studied the in vitro angiogenic response of human umbilical vein endothelial cells on the copper-doped titanium nitride (TiCuN) coating, which has been proved to own good antibacterial ability and excellent corrosion resistance as well as wear resistance. It was found that TiCuN coating had no cytotoxic effect and promoted the early cell proliferation, furthermore it significantly promoted the mRNA expressions of eNOS and VEGF, also obviously enhanced the cell migration and tube formation compared with TiN coating, which indicated that TiCuN coating can improve the angiogenesis ability of biomaterials and would gain new opportunities for the applications in orthopedic and cardiovascular fields. (C) 2020 Elsevier B.V. All rights reserved.
资助项目	National Key Research and Development Program of China[2018YFC1106601] ; National Key Research and Development Program of China[2016YFC1100601] ; LiaoNing Revitalization Talents Program[XLYC1807069] ; National Natural Science Foundation[51631009] ; National Natural Science Foundation[31870954] ; Key Projects for Foreign Cooperation of Bureau of International Cooperation Chinese Academy of Sciences[174321KYSB2018000]
WOS研究方向	Materials Science ; Physics
语种	英语
出版者	ELSEVIER
WOS记录号	WOS:000523600100014
资助机构	National Key Research and Development Program of China ; LiaoNing Revitalization Talents Program ; National Natural Science Foundation ; Key Projects for Foreign Cooperation of Bureau of International Cooperation Chinese Academy of Sciences
内容类型	期刊论文
源URL	[http://ir.imr.ac.cn/handle/321006/138038]
专题	金属研究所_中国科学院金属研究所
通讯作者	Zhao, Yanhui; Ren, Ling
作者单位	1.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China 2.Univ Sci & Technol China, Sch Mat Sci & Engn, Hefei 230026, Peoples R China 3.Nanjing Iron & Steel Co, Res Inst, Nanjing 210035, Peoples R China
推荐引用方式 GB/T 7714	Liu, Hui,Zhang, Xiyue,Jin, Shujing,et al. Effect of copper-doped titanium nitride coating on angiogenesis[J]. MATERIALS LETTERS,2020,269:4.
APA	Liu, Hui,Zhang, Xiyue,Jin, Shujing,Zhao, Yanhui,Ren, Ling,&Yang, Ke.(2020).Effect of copper-doped titanium nitride coating on angiogenesis.MATERIALS LETTERS,269,4.
MLA	Liu, Hui,et al."Effect of copper-doped titanium nitride coating on angiogenesis".MATERIALS LETTERS 269(2020):4.