Plasma spray of biofunctional (Mg, Sr)-substituted hydroxyapatite coatings for titanium alloy implants

doi:10.1016/j.jmst.2018.10.020

CORC > 金属研究所 > 中国科学院金属研究所

	Plasma spray of biofunctional (Mg, Sr)-substituted hydroxyapatite coatings for titanium alloy implants
	Cao, Lei 2,3; Ullah, Ihsan 2,4; Li, Na 2; Niu, Shiyu 5; Sun, Rujie 1; Xia, Dandan 5; Yang, Rui 2,4; Zhang, Xing 2,4
刊名	JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
	2019-05-01
卷号	35 期号:5 页码:719-726
关键词	Plasma spray Hydroxyapatite Titanium alloys Biological functions Bonding strength
ISSN号	1005-0302
DOI	10.1016/j.jmst.2018.10.020
通讯作者	Zhang, Xing(xingzhang@imr.ac.cn)
英文摘要	Plasma-sprayed hydroxyapatite (HA) coatings have been widely utilized in load-bearing titanium alloy implants. In this study, Mg, Sr co-substituted HA ((Mg, Sr)-HA) nano-scale powders have been synthesized, which are further used to prepare (Mg, Sr)-HA coatings on Ti-6Al-4V alloys in order to improve the biological functions. The average size of (Mg, Sr)-HA nano particles is similar to 75 nm. The average bonding strength for (Mg, Sr)-HA coating and samples after heat treatment at 500 degrees C or 600 degrees C for 3h are 26.17 +/- 2.11 MPa, 36.07 +/- 4.48 MPa and 37.07 +/- 2.95 MPa, respectively. There is a significantly increase of bonding strength likely due to low residual stress after heated treatment. MC3T3-E1 cells show a high proliferation rate when cultured with (Mg, Sr)-HA coating extract compared to the normal culture medium, which also exhibit large extension and deposition of extracellular matrices when adhered on the coating surfaces. Thus, these (Mg, Sr)-HA coatings show high bonding strength and improved biological functions, which offer promising future applications in the fields of orthopedics and dentistry. (C) 2019 Published by Elsevier Ltd on behalf of The editorial office of Journal of Materials Science & Technology.
资助项目	National Key Research and Development Program of China from Ministry of Science and Technology[2016YFC1100502] ; College Students' Innovative Program of Liaoning Province[201310163023] ; Key Research Program of Frontier Sciences[QYZDY-SSW-JSC027] ; Hundred Talent Program from Chinese Academy of Sciences (CAS) ; Innovation Research Program from Institute of Metal Research, CAS[2015-ZD01]
WOS研究方向	Materials Science ; Metallurgy & Metallurgical Engineering
语种	英语
出版者	JOURNAL MATER SCI TECHNOL
WOS记录号	WOS:000460640200003
资助机构	National Key Research and Development Program of China from Ministry of Science and Technology ; College Students' Innovative Program of Liaoning Province ; Key Research Program of Frontier Sciences ; Hundred Talent Program from Chinese Academy of Sciences (CAS) ; Innovation Research Program from Institute of Metal Research, CAS
内容类型	期刊论文
源URL	[http://ir.imr.ac.cn/handle/321006/132397]
专题	金属研究所_中国科学院金属研究所
通讯作者	Zhang, Xing
作者单位	1.Univ Utah, Salt Lake City, UT 84112 USA 2.Chinese Acad Sci, Shenyang Natl Lab Mat Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Univ Sci & Technol China, Sch Mat Sci & Engn, Hefei 239056, Anhui, Peoples R China 5.Shenyang Pharmaceut Univ, Shenyang 110016, Liaoning, Peoples R China
推荐引用方式 GB/T 7714	Cao, Lei,Ullah, Ihsan,Li, Na,et al. Plasma spray of biofunctional (Mg, Sr)-substituted hydroxyapatite coatings for titanium alloy implants[J]. JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,2019,35(5):719-726.
APA	Cao, Lei.,Ullah, Ihsan.,Li, Na.,Niu, Shiyu.,Sun, Rujie.,...&Zhang, Xing.(2019).Plasma spray of biofunctional (Mg, Sr)-substituted hydroxyapatite coatings for titanium alloy implants.JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,35(5),719-726.
MLA	Cao, Lei,et al."Plasma spray of biofunctional (Mg, Sr)-substituted hydroxyapatite coatings for titanium alloy implants".JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY 35.5(2019):719-726.