Hemangiopericytomas: Spatial Intracranial Location in a Voxel-Based Mapping Study

doi:10.1111/jon.12701

	Hemangiopericytomas: Spatial Intracranial Location in a Voxel-Based Mapping Study
	Li, Lianwang 2; Song, Ming 3; Zhang, Chuanbao 2; Qian, Zenghui 2; Li, Yiming 2; Li, Runting 2; Li, Chao 2; Yang, Zhengyi 3; Zhou, Dabiao 1,2
刊名	JOURNAL OF NEUROIMAGING
	2020-04-01
页码	8
关键词	intracranial hemangiopericytomas MRI voxel-based mapping spatial distribution
ISSN号	1051-2284
DOI	10.1111/jon.12701
通讯作者	Yang, Zhengyi(zhengyi.yang@nlpr.ia.ac.cn) ; Zhou, Dabiao(dabiaozhou@163.com)
英文摘要	BACKGROUND AND PURPOSE To investigate the preferred location of intracranial hemangiopericytomas (IHPCs) with voxel-based mapping and 3-dimensional reconstruction from MRI data. METHODS Gadolinium-enhanced tumors of 258 primary and single IHPCs were segmented semi-automatically, followed by manual checking and editing of boundaries. The lesions were registered to Montreal Neurological Institute standard anatomical space, and heat-map and 3-dimensional rendered frequency images were generated. All tumors were then superimposed on the Anatomical Automatic Labeling (AAL) template to further investigate the difference in the tumor location based on the voxel-wise frequency of occurrence with respect to laterality, sex, age, and pathologic grade. RESULTS The 3-dimensional rendered images show that the tumors commonly located in the posterior cranial cavity, surrounding the tentorium. The posterior third of the superior sagittal sinus and the confluence of sinuses were commonly affected. According to the analysis of tumor occurrence frequency in the AAL template, IHPCs were mainly observed in the limbic lobe, occipital lobe, and cerebellum. Tumors in younger patients preferentially located in the right occipital region (P = .027), whereas those with higher pathological grade more often located in the left parietal lobe (P = .034). CONCLUSIONS This is the first voxel-based study to explore the predilection site of IHPCs. Our study suggests that these tumors commonly affect the posterior cranial cavity, adjoining the tentorium and venous sinus. Further research is needed to investigate the possible factors underlying these topographic preferences.
资助项目	Capital Health Development Research Project[PXM2020_ 026280_000007] ; National Natural Science Foundation of China[81671855]
WOS关键词	CENTRAL-NERVOUS-SYSTEM ; SOLITARY-FIBROUS TUMOR/HEMANGIOPERICYTOMA ; MENINGIOMAS ; CLASSIFICATION ; PERICYTES ; FEATURES ; TUMORS ; LOCALIZATION ; MUTATIONS ; CELLS
WOS研究方向	Neurosciences & Neurology ; Radiology, Nuclear Medicine & Medical Imaging
语种	英语
出版者	WILEY
WOS记录号	WOS:000522769700001
资助机构	Capital Health Development Research Project ; National Natural Science Foundation of China
内容类型	期刊论文
源URL	[http://ir.ia.ac.cn/handle/173211/38719]
专题	自动化研究所_脑网络组研究中心
通讯作者	Yang, Zhengyi; Zhou, Dabiao
作者单位	1.China Natl Clin Res Ctr Neurol Dis, Beijing, Peoples R China 2.Capital Med Univ, Beijing Tiantan Hosp, Dept Neurosurg, 119 South Fourth Ring West Rd, Beijing 100070, Peoples R China 3.Chinese Acad Sci, Inst Automat, Brainnetome Ctr, 95 Zhongguancun East Rd, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Li, Lianwang,Song, Ming,Zhang, Chuanbao,et al. Hemangiopericytomas: Spatial Intracranial Location in a Voxel-Based Mapping Study[J]. JOURNAL OF NEUROIMAGING,2020:8.
APA	Li, Lianwang.,Song, Ming.,Zhang, Chuanbao.,Qian, Zenghui.,Li, Yiming.,...&Zhou, Dabiao.(2020).Hemangiopericytomas: Spatial Intracranial Location in a Voxel-Based Mapping Study.JOURNAL OF NEUROIMAGING,8.
MLA	Li, Lianwang,et al."Hemangiopericytomas: Spatial Intracranial Location in a Voxel-Based Mapping Study".JOURNAL OF NEUROIMAGING (2020):8.