Secondary Metabolites with Agricultural Antagonistic Potentials from Beauveria felina, a Marine-Derived Entomopathogenic Fungus

doi:10.1021/acs.jafc.0c05696

CORC > 海洋研究所 > 中国科学院海洋研究所 > 实验海洋生物学重点实验室

	Secondary Metabolites with Agricultural Antagonistic Potentials from Beauveria felina, a Marine-Derived Entomopathogenic Fungus
	Du, Feng-Yu 1,4,5; Li, Xiao-Ming 1,4; Sun, Ze-Chun 3; Meng, Ling-Hong 1,4; Wang, Bin-Gui 1,2,4
刊名	JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
	2020-12-16
卷号	68 期号:50 页码:14824-14831
关键词	Beauveria felina agricultural antagonistic potential secondary metabolites antifungal activity herbicidal activity
ISSN号	0021-8561
DOI	10.1021/acs.jafc.0c05696
通讯作者	Wang, Bin-Gui(wangbg@ms.qdio.ac.cn)
英文摘要	Soil-borne pathogens and weeds could synergistically affect vegetable growth and result in serious losses. The investigation of antagonistic metabolites from a marine-derived entomopathogenic fungus, Beauveria felina, obtained polyhydroxy steroid (1), tricyclic diterpenoid (2), isaridin (3), and destruxin cyclodepsipeptides (4-6). The structures and absolute configurations of new 1-3 were elucidated by extensive spectroscopic and X-ray crystallographic analyses, as well as electronic circular dichroism (ECD) calculations. Compounds 1 and 2 showed antifungal activities against carbendazim-resistant strains of Botrytis cinerea, with the minimum inhibitory concentration (MIC) values ranging from 16 to 32 mu g/mL, which were significantly better than those of carbendazim (MIC = 256 mu g/mL). Compound 5 exhibited significant antagonistic activity against the radicle growth of Amaranthus retroflexus seedlings, which was almost identical to that of the positive control (2,4-dichlorophenoxyacetic acid). The structure-activity differences of 4-6 suggested that the CI atom in HMPA(1) and beta-Me in Pro(2) should be the key factors to their herbicidal activities. Besides, compounds 3-6 showed moderate nematicidal activities against Meloidogyne incognita. These antagonistic effects of 1-6 were first reported and further revealed the synergistically antagonistic potential of B. felina to be developed into the biopesticide.
资助项目	Natural Science Foundation of China[31270104] ; NSFCShandong Joint Fund for Marine Science Research Centers[U1606403] ; Taishan Scholar project from Shandong province[ts201511060]
WOS研究方向	Agriculture ; Chemistry ; Food Science & Technology
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000600204700010
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/169495]
专题	海洋研究所_实验海洋生物学重点实验室
通讯作者	Wang, Bin-Gui
作者单位	1.Chinese Acad Sci, Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao 266071, Peoples R China 3.Qingdao Agr Univ, Coll Chem & Pharm, Qingdao 266109, Peoples R China 4.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 5.Qingdao Agr Univ, Coll Chem & Pharmaceut Sci, Qingdao 266109, Peoples R China
推荐引用方式 GB/T 7714	Du, Feng-Yu,Li, Xiao-Ming,Sun, Ze-Chun,et al. Secondary Metabolites with Agricultural Antagonistic Potentials from Beauveria felina, a Marine-Derived Entomopathogenic Fungus[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2020,68(50):14824-14831.
APA	Du, Feng-Yu,Li, Xiao-Ming,Sun, Ze-Chun,Meng, Ling-Hong,&Wang, Bin-Gui.(2020).Secondary Metabolites with Agricultural Antagonistic Potentials from Beauveria felina, a Marine-Derived Entomopathogenic Fungus.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,68(50),14824-14831.
MLA	Du, Feng-Yu,et al."Secondary Metabolites with Agricultural Antagonistic Potentials from Beauveria felina, a Marine-Derived Entomopathogenic Fungus".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 68.50(2020):14824-14831.