Effects of the glutathione administration via dietary on intestinal microbiota of white shrimp, Penaeus vannamei, under cyclic hypoxia conditions

CORC > 海洋研究所 > 中国科学院海洋研究所 > 实验海洋生物学重点实验室

	Effects of the glutathione administration via dietary on intestinal microbiota of white shrimp, Penaeus vannamei, under cyclic hypoxia conditions
	Han, S. Y.3; Wang, L.4,5,6; Wang, Y. L.4; Chen, Y.4; Wang, B. J.4; Wang, M. Q.1,2; Lin, J.3
刊名	ISJ-INVERTEBRATE SURVIVAL JOURNAL
	2020
卷号	17 页码:36-50
关键词	Penaeus vannamei glutathione intestinal microbiota reactive oxygen species histology
ISSN号	1824-307X
通讯作者	Wang, B. J.() ; Wang, M. Q.(wangmengqiang@ouc.edu.cn) ; Lin, J.(17135525452@qq.com)
英文摘要	Environmental stress can impair the survival, growth performance, and intestinal environment of shrimp. The objective of this study was to investigate the effect of glutathione (GSH) on the survival, growth performance, intestinal oxidation, microbiota, and histology of shrimp under hypoxia. Four treatments were used: (1) normoxia, (2) cyclic serious/medium hypoxia (CSMH), (3) CSMH and 75 mg kg(-1) GSH, and (4) CSMH and 150 mg kg(-1) GSH. White shrimp (Penaeus vannamei) in groups 3 and 4 were fed a commercial diet supplemented with 75 and 150 mg kg(-1) GSH for a 28 day period, respectively, and they were cultured under CSMH (0.8 - 3.5 mg L-1 dissolved oxygen) for the last 14 days of the experiment. P. vannamei supplemented with 75 mg kg(-1) GSH showed significantly improved survival and growth performance under CSMH compared with the CSMH condition alone. The dose of 75 mg kg(-1) GSH completely eliminated overproduction of reactive oxygen species and malondialdehyde to suppress serious histopathological lesions and improve bacterial diversity and the relative abundance of beneficial bacteria, such as Rhodobacteraceae, thereby preventing pathogen (e.g., Vibrio) invasion in the intestine of shrimp under CSMH. However, the dose of 150 mg kg(-1) GSH was excessive, as it led to serious impairment of survival and growth. These results indicate that 75 mg kg(-1) GSH has the potential to control shrimp mortality and growth inhibition under CSMH in the shrimp farm setting.
资助项目	National Natural Science Foundation of China-Joint Fund of Shandong People's Government[U1706209] ; Chinese Academy of Sciences STS Regional Center Project (Fujian Province)
WOS研究方向	Immunology ; Zoology
语种	英语
出版者	INVERTEBRATE SURVIVAL JOURNAL
WOS记录号	WOS:000531792500001
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/167439]
专题	海洋研究所_实验海洋生物学重点实验室
通讯作者	Wang, B. J.; Wang, M. Q.; Lin, J.
作者单位	1.Ocean Univ China, MOE Key Lab Marine Genet & Breeding, Qingdao 266003, Peoples R China 2.Natl Lab Marine Sci & Technol, Ctr Marine Mol Biotechnol, Qingdao 266237, Peoples R China 3.Guangxi Univ Chinese Med, Fac Basic Med, Nanning 530001, Peoples R China 4.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 5.Chinese Acad Sci, CAS Ctr Ocean Megasci, Qingdao 266400, Peoples R China 6.Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266237, Peoples R China
推荐引用方式 GB/T 7714	Han, S. Y.,Wang, L.,Wang, Y. L.,et al. Effects of the glutathione administration via dietary on intestinal microbiota of white shrimp, Penaeus vannamei, under cyclic hypoxia conditions[J]. ISJ-INVERTEBRATE SURVIVAL JOURNAL,2020,17:36-50.
APA	Han, S. Y..,Wang, L..,Wang, Y. L..,Chen, Y..,Wang, B. J..,...&Lin, J..(2020).Effects of the glutathione administration via dietary on intestinal microbiota of white shrimp, Penaeus vannamei, under cyclic hypoxia conditions.ISJ-INVERTEBRATE SURVIVAL JOURNAL,17,36-50.
MLA	Han, S. Y.,et al."Effects of the glutathione administration via dietary on intestinal microbiota of white shrimp, Penaeus vannamei, under cyclic hypoxia conditions".ISJ-INVERTEBRATE SURVIVAL JOURNAL 17(2020):36-50.