Cyclonerane sesquiterpenes and an isocoumarin derivative from the marine-alga-endophytic fungus Trichoderma citrinoviride A-WH-20-3

doi:10.1016/j.fitote.2020.104469

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	Cyclonerane sesquiterpenes and an isocoumarin derivative from the marine-alga-endophytic fungus Trichoderma citrinoviride A-WH-20-3
	Liu, Xiang-Hong 1,2,3; Hou, Xu-Liang 1,3; Song, Yin-Ping 1; Wang, Bin-Gui 1,2; Ji, Nai-Yun 1
刊名	FITOTERAPIA
	2020-03-01
卷号	141 页码:4
关键词	Trichoderma Terpene Sesquiterpene Cyclonerane Isocoumarin
ISSN号	0367-326X
DOI	10.1016/j.fitote.2020.104469
通讯作者	Ji, Nai-Yun(nyji@yic.ac.cn)
英文摘要	Two new cyclonerane sesquiterpenes, (10E)-isocyclonerotriol (1) and (10Z)-isocyclonerotriol (2), and one new isocoumarin derivative, trichophenol A (3), were isolated from Trichoderma citrinoviride A-WH-20-3, an endophyte from the marine red alga Laurencia okamurai. Their structures and relative configurations were assigned by spectroscopic techniques, highlighted by using Sarotti's DP4+ sheet to confirm the cyclopentane ring. The absolute configuration of 1 was established by comparison of experimental and calculated specific rotation data. Compounds 1 and 2 represent the first occurrence of ring-isomerized cycloneranes. Compound 3 is the first 3-phenylisocoumarin derivative from Trichoderma and features inhibition of several marine-derived bacteria and phytoplankton species.
资助项目	Natural Science Foundation for Distinguished Young Scholars of Shandong Province[JQ201712] ; National Natural Science Foundation of China[31670355] ; Youth Innovation Promotion Association of CAS[2013138] ; Shuangbai Plan of Yantai[2018-3] ; Taishan Scholar Project Special Funding[tsqn201909164]
WOS研究方向	Pharmacology & Pharmacy
语种	英语
出版者	ELSEVIER
WOS记录号	WOS:000518703900012
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/165834]
专题	海洋研究所_实验海洋生物学重点实验室
通讯作者	Ji, Nai-Yun
作者单位	1.Chinese Acad Sci, Ctr Ocean Mega Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 2.Chinese Acad Sci, Lab Marine Biol & Biotechnol, Qingdao Natl Lab Marine Sci & Technol, Key Lab Expt Marine Biol,Inst Oceanol, Qingdao 266071, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Liu, Xiang-Hong,Hou, Xu-Liang,Song, Yin-Ping,et al. Cyclonerane sesquiterpenes and an isocoumarin derivative from the marine-alga-endophytic fungus Trichoderma citrinoviride A-WH-20-3[J]. FITOTERAPIA,2020,141:4.
APA	Liu, Xiang-Hong,Hou, Xu-Liang,Song, Yin-Ping,Wang, Bin-Gui,&Ji, Nai-Yun.(2020).Cyclonerane sesquiterpenes and an isocoumarin derivative from the marine-alga-endophytic fungus Trichoderma citrinoviride A-WH-20-3.FITOTERAPIA,141,4.
MLA	Liu, Xiang-Hong,et al."Cyclonerane sesquiterpenes and an isocoumarin derivative from the marine-alga-endophytic fungus Trichoderma citrinoviride A-WH-20-3".FITOTERAPIA 141(2020):4.