Rapid nitrate determination with a portable lab-on-chip device based on double microstructured assisted reactors

doi:10.1039/d0lc01057j

CORC > 海洋研究所 > 中国科学院海洋研究所

	Rapid nitrate determination with a portable lab-on-chip device based on double microstructured assisted reactors
	Wang, Fang 1,4; Zhu, Jiaomeng 1,4; Hu, Xuejia 1,4; Chen, Longfei 1,4; Zuo, Yunfeng 1,4; Yang, Yi 1,4; Jiang, Fenghua 3; Sun, Chengjun 3; Zhao, Weihong 2; Han, Xiaotian 2
刊名	LAB ON A CHIP
	2021-03-21
卷号	21 期号:6 页码:1109-1117
ISSN号	1473-0197
DOI	10.1039/d0lc01057j
通讯作者	Yang, Yi(yangyiys@whu.edu.cn)
英文摘要	Determining the nitrate levels is critical for water quality monitoring, and traditional methods are limited by high toxicity and low detection efficiency. Here, rapid nitrate determination was realized using a portable device based on innovative three-dimensional double microstructured assisted reactors (DMARs). On-chip nitrate reduction and chromogenic reaction were conducted in the DMARs, and the reaction products then flowed into a PMMA optical detection chip for absorbance measurement. A significant enhancement of reaction rate and efficiency was observed in the DMARs due to their sizeable surface-area-to-volume ratios and hydrodynamics in the microchannels. The highest reduction ratio of 94.8% was realized by optimizing experimental parameters, which is greatly improved compared to conventional zinc-cadmium based approaches. Besides, modular optical detection improves the reliability of the portable device, and a smartphone was used to achieve a portable and convenient nitrate analysis. Different water samples were successfully analysed using the portable device based on DMARs. The results demonstrated that the device features fast detection (115 s per sample), low reagent consumptions (26.8 mu L per sample), particularly low consumptions of toxic reagents (0.38 mu L per sample), good reproducibility and low relative standard deviations (RSDs, 0.5-1.38%). Predictably, the portable lab-on-chip device based on microstructured assisted reactors will find more applications in the field of water quality monitoring in the near future.
资助项目	National Natural Science Foundation of China[11774274] ; National Key R&D Program of China[2018YFC1003200] ; Foundation Research Fund of Shenzhen Science and Technology Program[JCYJ20170818112939064] ; Open Financial Grant from Qingdao National Laboratory for Marine Science and Technology[QNLM2016ORP0410]
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry ; Science & Technology - Other Topics ; Instruments & Instrumentation
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000632163600006
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/170347]
专题	中国科学院海洋研究所
通讯作者	Yang, Yi
作者单位	1.Wuhan Univ, Sch Phys & Technol, Minist Educ, Key Lab Artificial Micro & Nanostruct, Wuhan 430072, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Beijing, Peoples R China 3.First Inst Oceanog, MNR, Shenzhen, Peoples R China 4.Wuhan Univ, Shenzhen Res Inst, Shenzhen 518000, Peoples R China
推荐引用方式 GB/T 7714	Wang, Fang,Zhu, Jiaomeng,Hu, Xuejia,et al. Rapid nitrate determination with a portable lab-on-chip device based on double microstructured assisted reactors[J]. LAB ON A CHIP,2021,21(6):1109-1117.
APA	Wang, Fang.,Zhu, Jiaomeng.,Hu, Xuejia.,Chen, Longfei.,Zuo, Yunfeng.,...&Han, Xiaotian.(2021).Rapid nitrate determination with a portable lab-on-chip device based on double microstructured assisted reactors.LAB ON A CHIP,21(6),1109-1117.
MLA	Wang, Fang,et al."Rapid nitrate determination with a portable lab-on-chip device based on double microstructured assisted reactors".LAB ON A CHIP 21.6(2021):1109-1117.