Chemical synthesis of marine saponins

doi:10.1039/c8np00087e

	Chemical synthesis of marine saponins
	Xiao,Guozhi; Shao,Xiaofei; Zhu,Dapeng; Yu,Biao
刊名	NATURAL PRODUCT REPORTS
	2019
卷号	36 期号:5 页码:769-787
ISSN号	0265-0568
DOI	10.1039/c8np00087e
英文摘要	Saponins are characteristic metabolites of starfish and sea cucumbers, and occasionally are also found in sponges, soft coral, and small fish. These steroid or triterpenoid glycosides often show remarkable biological and pharmacological activities, such as antifungal, antifouling, shark repellent, antitumor and anti- inflammatory activities. Over one thousand marine saponins have been characterized; the majority of them can be categorized into three major structural types, i.e., asterosaponins, polyhydroxysteroid glycosides, and holostane glycosides. Thus far, only 12 marine saponins have been synthesized; those representing the major types were successfully synthesized recently. The syntheses involve preparation of the aglycones from the terrestrial steroid or triterpene materials, installation of the carbohydrate units, and manipulation of the protecting groups. Herein, we provide a comprehensive review on these syntheses.
WOS记录号	WOS:000468788800003
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/71105]
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Xiao,Guozhi,Shao,Xiaofei,Zhu,Dapeng,et al. Chemical synthesis of marine saponins[J]. NATURAL PRODUCT REPORTS,2019,36(5):769-787.
APA	Xiao,Guozhi,Shao,Xiaofei,Zhu,Dapeng,&Yu,Biao.(2019).Chemical synthesis of marine saponins.NATURAL PRODUCT REPORTS,36(5),769-787.
MLA	Xiao,Guozhi,et al."Chemical synthesis of marine saponins".NATURAL PRODUCT REPORTS 36.5(2019):769-787.