Applications of inorganic nanoparticles in the diagnosis and therapy of atherosclerosis

doi:10.1039/d0bm00196a

CORC > 宁波材料技术与工程研究所 > 中国科学院宁波材料技术与工程研究所 > 2020专题

	Applications of inorganic nanoparticles in the diagnosis and therapy of atherosclerosis
	Dai, Ting ; He, Wenming ; Yao, Chenyang ; Ma, Xuehua ; Ren, Wenzhi ; Mai, Yifeng ; Wu, Aiguo
刊名	BIOMATERIALS SCIENCE
	2020
卷号	8 期号:14 页码:3784-3799
关键词	MEDIATED SONODYNAMIC THERAPY PHOTODYNAMIC THERAPY IN-VIVO GOLD NANOPARTICLES FOAM CELLS ANIMAL ATHEROSCLEROSIS THERANOSTIC PLATFORM SCIENTIFIC STATEMENT PHOTOTHERMAL THERAPY INTIMAL HYPERPLASIA
DOI	10.1039/d0bm00196a
英文摘要	Atherosclerosis is a chronic progressive disease, which may result in serious clinical outcomes, such as acute heart events or stroke with high mortality. At present, the clinical problems of atherosclerosis mainly consist of the difficulty in confirming the plaques or identifying the stability of the plaques in the early phase and the shortage of valid treatments. Fortunately, with the development of nanotechnology, various inorganic nanoparticles with imaging enhancement and noninvasive therapy functions have been studied in the imaging and treatment of atherosclerosis, which has brought new hope to patients. This review focuses on the recent progress in the use of inorganic nanoparticles in the diagnosis and therapy of atherosclerosis, including the key processes in the development of atherosclerosis and the mainly involved cells, inorganic nanoparticle-based dual-mode imaging methods classified by the types of targeting cells, and inorganic nanoparticle-based therapeutic approaches, such as photothermal therapy (PTT), photodynamic therapy (PDT), sonodynamic therapy (SDT), drug delivery, gene therapy and imaging-guided therapy for atherosclerosis. Finally, this review discusses the challenges and directions of inorganic nanoparticles in potential clinical translation of anti-atherosclerosis in future. We believe this review will enable readers to systematically understand the progress of the inorganic nanoparticle-based imaging and therapy of atherosclerosis and therefore promote the further development of anti-atherosclerosis.
学科主题	Materials Science
内容类型	期刊论文
源URL	[http://ir.nimte.ac.cn/handle/174433/20643]
专题	2020专题
作者单位	1.Ren, WZ (corresponding author), Key Lab Diag & Treatment Digest Syst Tumors Zheji, 175 Yongfeng North Rd, Ningbo 315016, Zhejiang, Peoples R China. 2.Ren, WZ (corresponding author), Chinese Acad Sci, Cixi Inst Biomed Engn, Key Lab Magnet Mat & Devices, 1219 ZhongGuan West Rd, Ningbo 315201, Zhejiang, Peoples R China. 3.Ren, WZ (corresponding author), Chinese Acad Sci, Zhejiang Engn Res Ctr Biomed Mat, Ningbo Inst Mat Technol & Engn, 1219 ZhongGuan West Rd, Ningbo 315201, Zhejiang, Peoples R China. 4.Mai, YF (corresponding author), Ningbo Univ, Med Sch, Affiliated Hosp, Dept Cardiol, 247 Renmin Rd, Ningbo 315020, Zhejiang, Peoples R China.
推荐引用方式 GB/T 7714	Dai, Ting,He, Wenming,Yao, Chenyang,et al. Applications of inorganic nanoparticles in the diagnosis and therapy of atherosclerosis[J]. BIOMATERIALS SCIENCE,2020,8(14):3784-3799.
APA	Dai, Ting.,He, Wenming.,Yao, Chenyang.,Ma, Xuehua.,Ren, Wenzhi.,...&Wu, Aiguo.(2020).Applications of inorganic nanoparticles in the diagnosis and therapy of atherosclerosis.BIOMATERIALS SCIENCE,8(14),3784-3799.
MLA	Dai, Ting,et al."Applications of inorganic nanoparticles in the diagnosis and therapy of atherosclerosis".BIOMATERIALS SCIENCE 8.14(2020):3784-3799.