NPInter v4.0: an integrated database of ncRNA interactions | |
Teng, Xueyi3,4; Chen, Xiaomin3,4; Xue, Hua3,4; Tang, Yiheng3,4; Zhang, Peng3; Kang, Quan3; Hao, Yajing3,4; Chen, Runsheng2,3,4; Zhao, Yi1; He, Shunmin3,4 | |
刊名 | NUCLEIC ACIDS RESEARCH |
2020-01-08 | |
卷号 | 48期号:D1页码:D160-D165 |
ISSN号 | 0305-1048 |
DOI | 10.1093/nar/gkz969 |
英文摘要 | Noncoding RNAs (ncRNAs) play crucial regulatory roles in a variety of biological circuits. To document regulatory interactions between ncRNAs and biomolecules, we previously created the NPInter database (http://bigdata.ibp.ac.cn/npinter). Since the last version of NPInter was issued, a rapidly growing number of studies have reported novel interactions and accumulated numerous high-throughput interactome data. We have therefore updated NPInter to its fourth edition in which are integrated 600 000 new experimentally identified ncRNA interactions. ncRNA-DNA interactions derived from ChIRP-seq data and circular RNA interactions have been included in the database. Additionally, disease associations were annotated to the interactingmolecules. The database website has also been redesigned with a more user-friendly interface and several additional functional modules. Overall, NPInter v4.0 now provides more comprehensive data and services for researchers working on ncRNAs and their interactions with other biomolecules. |
资助项目 | National Natural Science Foundation of China[31701117] ; National Natural Science Foundation of China[31970647] ; National Key R&D Program of China[2016YFC0901702] ; National Key R&D Program of China[2017YFC0907503] ; 13th Five-Year Informatization Plan of Chinese Academy of Sciences[XXH13505-05] |
WOS研究方向 | Biochemistry & Molecular Biology |
语种 | 英语 |
出版者 | OXFORD UNIV PRESS |
WOS记录号 | WOS:000525956700024 |
内容类型 | 期刊论文 |
源URL | [http://119.78.100.204/handle/2XEOYT63/14245] |
专题 | 中国科学院计算技术研究所期刊论文_英文 |
通讯作者 | Chen, Runsheng; Zhao, Yi; He, Shunmin |
作者单位 | 1.Chinese Acad Sci, Adv Comp Res Ctr, Inst Comp Technol, Key Lab Intelligent Informat Proc,Bioinformat Res, Beijing 100190, Peoples R China 2.Guangdong Geneway Decoding Biotech Co Ltd, Foshan 528316, Peoples R China 3.Chinese Acad Sci, Ctr Big Data Res Hlth, Inst Biophys, Key Lab RNA Biol, Beijing 100101, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Teng, Xueyi,Chen, Xiaomin,Xue, Hua,et al. NPInter v4.0: an integrated database of ncRNA interactions[J]. NUCLEIC ACIDS RESEARCH,2020,48(D1):D160-D165. |
APA | Teng, Xueyi.,Chen, Xiaomin.,Xue, Hua.,Tang, Yiheng.,Zhang, Peng.,...&He, Shunmin.(2020).NPInter v4.0: an integrated database of ncRNA interactions.NUCLEIC ACIDS RESEARCH,48(D1),D160-D165. |
MLA | Teng, Xueyi,et al."NPInter v4.0: an integrated database of ncRNA interactions".NUCLEIC ACIDS RESEARCH 48.D1(2020):D160-D165. |
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