NPInter v4.0: an integrated database of ncRNA interactions
Teng, Xueyi3,4; Chen, Xiaomin3,4; Xue, Hua3,4; Tang, Yiheng3,4; Zhang, Peng3; Kang, Quan3; Hao, Yajing3,4; Chen, Runsheng2,3,4; Zhao, Yi1; He, Shunmin3,4
刊名NUCLEIC ACIDS RESEARCH
2020-01-08
卷号48期号:D1页码:D160-D165
ISSN号0305-1048
DOI10.1093/nar/gkz969
英文摘要Noncoding RNAs (ncRNAs) play crucial regulatory roles in a variety of biological circuits. To document regulatory interactions between ncRNAs and biomolecules, we previously created the NPInter database (http://bigdata.ibp.ac.cn/npinter). Since the last version of NPInter was issued, a rapidly growing number of studies have reported novel interactions and accumulated numerous high-throughput interactome data. We have therefore updated NPInter to its fourth edition in which are integrated 600 000 new experimentally identified ncRNA interactions. ncRNA-DNA interactions derived from ChIRP-seq data and circular RNA interactions have been included in the database. Additionally, disease associations were annotated to the interactingmolecules. The database website has also been redesigned with a more user-friendly interface and several additional functional modules. Overall, NPInter v4.0 now provides more comprehensive data and services for researchers working on ncRNAs and their interactions with other biomolecules.
资助项目National Natural Science Foundation of China[31701117] ; National Natural Science Foundation of China[31970647] ; National Key R&D Program of China[2016YFC0901702] ; National Key R&D Program of China[2017YFC0907503] ; 13th Five-Year Informatization Plan of Chinese Academy of Sciences[XXH13505-05]
WOS研究方向Biochemistry & Molecular Biology
语种英语
出版者OXFORD UNIV PRESS
WOS记录号WOS:000525956700024
内容类型期刊论文
源URL[http://119.78.100.204/handle/2XEOYT63/14245]  
专题中国科学院计算技术研究所期刊论文_英文
通讯作者Chen, Runsheng; Zhao, Yi; He, Shunmin
作者单位1.Chinese Acad Sci, Adv Comp Res Ctr, Inst Comp Technol, Key Lab Intelligent Informat Proc,Bioinformat Res, Beijing 100190, Peoples R China
2.Guangdong Geneway Decoding Biotech Co Ltd, Foshan 528316, Peoples R China
3.Chinese Acad Sci, Ctr Big Data Res Hlth, Inst Biophys, Key Lab RNA Biol, Beijing 100101, Peoples R China
4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714
Teng, Xueyi,Chen, Xiaomin,Xue, Hua,et al. NPInter v4.0: an integrated database of ncRNA interactions[J]. NUCLEIC ACIDS RESEARCH,2020,48(D1):D160-D165.
APA Teng, Xueyi.,Chen, Xiaomin.,Xue, Hua.,Tang, Yiheng.,Zhang, Peng.,...&He, Shunmin.(2020).NPInter v4.0: an integrated database of ncRNA interactions.NUCLEIC ACIDS RESEARCH,48(D1),D160-D165.
MLA Teng, Xueyi,et al."NPInter v4.0: an integrated database of ncRNA interactions".NUCLEIC ACIDS RESEARCH 48.D1(2020):D160-D165.
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