Early-Life Conditions and Cognitive Function in Middle-and Old-Aged Chinese Adults: A Longitudinal Study

doi:10.3390/ijerph17103451

	Early-Life Conditions and Cognitive Function in Middle-and Old-Aged Chinese Adults: A Longitudinal Study
	Yang, Lei 1; Wang, Zhenbo 2
刊名	INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
	2020-05-01
卷号	17 期号:10 页码:13
关键词	childhood conditions childhood socioeconomic status cognitive function early parental death China Health and Retirement Longitudinal Study (CHARLS)
DOI	10.3390/ijerph17103451
通讯作者	Wang, Zhenbo(wangzb@igsnrr.ac.cn)
英文摘要	A range of previous studies have suggested that early-life conditions (ELCs) are associated with various health problems throughout life in Western societies. The aim of this study was to investigate whether, and how, early-life conditions predicted the level and trajectory of cognitive function in middle- and old-aged Chinese adults. Data were obtained from China Health and Retirement Longitudinal Study which comprised 16,258 adults at baseline. Cognitive function was assessed using mental intactness and episodic memory and ELCs were measured by early parental death, childhood socioeconomic status (SES), food deprivation, and childhood health. Growth curve modeling was used to examine the trajectory of cognitive function (three waves in a 6-year period)with particular attention paid to the effects of ELCs on cognition. The results show that early maternal death is associated with the baseline cognitive level among middle- and old-aged Chinese adults (beta range between -0.44 and -0.35, p < 0.05), but that this association is also largely attenuated by adulthood education. Higher childhood SES predicts an enhanced level of baseline cognition in both age groups (beta range between 0.08 and 1.27, p < 0.001), but only protects against cognitive decline at baseline in middle-aged adults. Participants who were less healthy during childhood tended to have lower cognitive performance than those who had enjoyed good health (beta range between -0.36 and -0.14, p < 0.05). The results of this study highlight the detrimental impact of deleterious ELCs on cognitive function throughout later life.
资助项目	Ministry of Education of China for Youth Project of Humanities and Social Sciences Research[19YJC840053] ; National Social Science Foundation of China[19ZDA358]
WOS关键词	SOCIOECONOMIC POSITION ; DEPRESSIVE SYMPTOMS ; CHILDHOOD ADVERSITY ; HEALTH ; CONSEQUENCES ; DEPRIVATION ; ENVIRONMENT ; RETIREMENT ; DECLINE ; GENDER
WOS研究方向	Environmental Sciences & Ecology ; Public, Environmental & Occupational Health
语种	英语
出版者	MDPI
WOS记录号	WOS:000539300900108
资助机构	Ministry of Education of China for Youth Project of Humanities and Social Sciences Research ; National Social Science Foundation of China
内容类型	期刊论文
源URL	[http://ir.igsnrr.ac.cn/handle/311030/162404]
专题	中国科学院地理科学与资源研究所
通讯作者	Wang, Zhenbo
作者单位	1.Minzu Univ China, Sch Ethnol & Sociol, Beijing 100081, Peoples R China 2.Chinese Acad Sci, Inst Geog Sci & Nat Resources Res, Beijing 100101, Peoples R China
推荐引用方式 GB/T 7714	Yang, Lei,Wang, Zhenbo. Early-Life Conditions and Cognitive Function in Middle-and Old-Aged Chinese Adults: A Longitudinal Study[J]. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH,2020,17(10):13.
APA	Yang, Lei,&Wang, Zhenbo.(2020).Early-Life Conditions and Cognitive Function in Middle-and Old-Aged Chinese Adults: A Longitudinal Study.INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH,17(10),13.
MLA	Yang, Lei,et al."Early-Life Conditions and Cognitive Function in Middle-and Old-Aged Chinese Adults: A Longitudinal Study".INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH 17.10(2020):13.