Association between Selenium in Soil and Diabetes in Chinese Residents Aged 35-74 Years: Results from the 2010 National Survey of Chronic Diseases and Behavioral Risk Factors Surveillance

doi:10.3967/bes2020.035

	Association between Selenium in Soil and Diabetes in Chinese Residents Aged 35-74 Years: Results from the 2010 National Survey of Chronic Diseases and Behavioral Risk Factors Surveillance
	Wang Qi Qi 1; Yu Shi Cheng 1; Xu Cheng Dong 6; Liu Jian Jun 1; Li Yuan Qiu 1; Zhang Man Hui 5; Long Xiao Juan 1; Liu Yun Ning 4; Bi Yu Fang 3; Zhao Wen Hua 2
刊名	BIOMEDICAL AND ENVIRONMENTAL SCIENCES
	2020-04-01
卷号	33 期号:4 页码:260-268
关键词	Selenium Diabetes Odds ratio Behavioral risk factors Survey
ISSN号	0895-3988
DOI	10.3967/bes2020.035
通讯作者	Bi Yu Fang(byf10784@rjh.com.cn) ; Zhao Wen Hua(zhaowh@chinacdc.cn) ; Yao Hong Yan(yaohy@chinacdc.cn)
英文摘要	Objective To explore the association between soil selenium levels and the risk of diabetes in Chinese adults aged 35-74 years. Methods Data for this study were derived from the China Chronic Diseases and Behavioral Risk Factors Surveillance 2010 survey. Selenium concentrations in soil were obtained from the Atlas of Soil Environmental Background Values in China. A two-level binary logistic regression model was used to determine the association between soil selenium concentrations and the risk of diabetes, with participants nested within districts/counties. Results A total of 69,332 participants aged 35-74 years, from 158 districts/counties were included in the analysis. Concentrations of selenium in soil varied greatly across the 158 districts/counties, with a median concentration of 0.219 mg/kg (IQR: 0.185-0.248). The results showed that both Quartile 1 (0.119-0.185 mg/kg) and Quartile 4 (0.249-0.344 mg/kg) groups were positively associated with diabetes compared to a soil selenium concentration of 0.186-0.219 mg/kg (Quartile 2), crude odds ratios (ORs) (95% CI) were 1.227 (1.003-1.502) and 1.280 (1.048-1.563). The P values were 0.045 and 0.013, for Quartile 1 and Quartile 4 groups, respectively. After adjusting for all confounding factors of interest, the Quartile 1 group became non-significant, and the Quartile 4 group had an adjusted OR (95% CI) of 1.203 (1.018-1.421) relative to the reference group (Quartile 2), the P values was 0.030. No significant results were seen for the Quartile 3 group (0.220-0.248 mg/kg) compared to the reference group. Conclusion Excessive selenium concentrations in soil could increase the risk of diabetes among Chinese adults aged 35-74 years.
资助项目	National Key Research and Development Programme[2018YFC1315305] ; China CDC's Scientific Research Project[JY18-2-22] ; China CDC's Public Health and Emergency Response Mechanism Programme[131031001000150001]
WOS关键词	HEALTH
WOS研究方向	Environmental Sciences & Ecology ; Public, Environmental & Occupational Health
语种	英语
出版者	CHINESE CENTER DISEASE CONTROL & PREVENTION
WOS记录号	WOS:000539379000005
资助机构	National Key Research and Development Programme ; China CDC's Scientific Research Project ; China CDC's Public Health and Emergency Response Mechanism Programme
内容类型	期刊论文
源URL	[http://ir.igsnrr.ac.cn/handle/311030/162256]
专题	中国科学院地理科学与资源研究所
通讯作者	Bi Yu Fang; Zhao Wen Hua; Yao Hong Yan
作者单位	1.Chinese Ctr Dis Control & Prevent, Beijing 102206, Peoples R China 2.Chinese Ctr Dis Control & Prevent, Natl Inst Nutr & Hlth, Beijing 100050, Peoples R China 3.Shanghai Jiao Tong Univ, Ruijin Hosp, Shanghai Inst Endocrine & Metab Dis, Sch Med,Shanghai Natl Clin Res Ctr Endocrine & Me, Shanghai 200025, Peoples R China 4.Chinese Ctr Dis Control & Prevent, Natl Ctr Chron & Non communicable Dis Control & P, Beijing 100050, Peoples R China 5.Peking Univ, Hosp 3, Beijing 100191, Peoples R China 6.Chinese Acad Sci, Inst Geog Sci & Nat Resources Res, State Key Lab Resources & Environm Informat Syst, Beijing 100101, Peoples R China
推荐引用方式 GB/T 7714	Wang Qi Qi,Yu Shi Cheng,Xu Cheng Dong,et al. Association between Selenium in Soil and Diabetes in Chinese Residents Aged 35-74 Years: Results from the 2010 National Survey of Chronic Diseases and Behavioral Risk Factors Surveillance[J]. BIOMEDICAL AND ENVIRONMENTAL SCIENCES,2020,33(4):260-268.
APA	Wang Qi Qi.,Yu Shi Cheng.,Xu Cheng Dong.,Liu Jian Jun.,Li Yuan Qiu.,...&Yao Hong Yan.(2020).Association between Selenium in Soil and Diabetes in Chinese Residents Aged 35-74 Years: Results from the 2010 National Survey of Chronic Diseases and Behavioral Risk Factors Surveillance.BIOMEDICAL AND ENVIRONMENTAL SCIENCES,33(4),260-268.
MLA	Wang Qi Qi,et al."Association between Selenium in Soil and Diabetes in Chinese Residents Aged 35-74 Years: Results from the 2010 National Survey of Chronic Diseases and Behavioral Risk Factors Surveillance".BIOMEDICAL AND ENVIRONMENTAL SCIENCES 33.4(2020):260-268.