Changes in urinary arsenic species and methylation capacity in original arsenic exposure cohort after water quality improvement

doi:10.1007/s10653-020-00523-4

	Changes in urinary arsenic species and methylation capacity in original arsenic exposure cohort after water quality improvement
	Kong, Chang 1,2; Yang, Linsheng 1,2; Yu, Jiangping 1; Li, Hairong 1,2; Wei, Binggan 1; Guo, Zhiwei 3; Xia, Yajuan 3; Wu, Kegong 3
刊名	ENVIRONMENTAL GEOCHEMISTRY AND HEALTH
	2020-02-07
页码	11
关键词	Arsenic Methylation capacity Water quality improvement Drinking groundwater Change
ISSN号	0269-4042
DOI	10.1007/s10653-020-00523-4
通讯作者	Wei, Binggan(weibg@igsnrr.ac.cn)
英文摘要	Water quality improvement is the most efficient way to prevent arsenic exposure. After the cessation of arsenic ingestion, arsenic methylation capacity of the exposed population can change significantly. The factors associated with these changes remain poorly understood. Therefore, arsenic methylation capacity in a study cohort was estimated before and after water quality improvement in the present study. Results indicated that urinary content of the arsenic species in the study cohort significantly decreased after water quality improvement. In addition, the proportions of inorganic arsenic (%iAs) and monomethyl arsenic acid (%MMA) were significantly decreased, while proportions of dimethyl arsenic (%DMA) increased. The primary methylation index (PMI) and secondary methylation index (SMI) increased from 0.85 to 0.92 and 0.82 to 0.84, respectively. Arsenic species urinary content and arsenic methylation index varied slightly between the study cohort after water quality improvement and the control cohort. The rate of increase in PMI was higher than that in SMI. The study group aged 31-50 years had the highest increase in PMI. Logistic regression revealed that %DMA before water quality improvement was negatively associated with the increase in PMI, while %iAs were positively related, and %MMA were positively associated with the increase in SMI. It is concluded that urinary arsenic species content and arsenic methylation capacity increased to the levels of the control cohort after water quality improvement. An increase in primary arsenic methylation capacity may be a burden on the secondary arsenic methylation capacity. The main role of arsenic methylation capacity recovery may be the cessation of arsenic exposure.
资助项目	National Natural Science Foundation of China[41601559] ; State Key Program of National Natural Science of China[41230749] ; Health and Family Planning Project of Inner Mongolia[201702045]
WOS关键词	ONE-CARBON METABOLISM ; INNER-MONGOLIA ; CHILDREN ; HEALTH ; GROUNDWATER ; ASSOCIATION ; SPECIATION ; ADULTS ; RISK
WOS研究方向	Engineering ; Environmental Sciences & Ecology ; Public, Environmental & Occupational Health ; Water Resources
语种	英语
出版者	SPRINGER
WOS记录号	WOS:000515943900001
资助机构	National Natural Science Foundation of China ; State Key Program of National Natural Science of China ; Health and Family Planning Project of Inner Mongolia
内容类型	期刊论文
源URL	[http://ir.igsnrr.ac.cn/handle/311030/132847]
专题	中国科学院地理科学与资源研究所
通讯作者	Wei, Binggan
作者单位	1.Chinese Acad Sci, Key Lab Land Surface Pattern & Simulat, Inst Geog Sci & Nat Resources Res, 11 A Datun Rd, Beijing 100101, Peoples R China 2.Univ Chinese Acad Sci, Coll Resources & Environm, Huairou, Peoples R China 3.Inner Mongolia Comprehens Ctr Dis Control & Preve, Hohhot, Inner Mongolia, Peoples R China
推荐引用方式 GB/T 7714	Kong, Chang,Yang, Linsheng,Yu, Jiangping,et al. Changes in urinary arsenic species and methylation capacity in original arsenic exposure cohort after water quality improvement[J]. ENVIRONMENTAL GEOCHEMISTRY AND HEALTH,2020:11.
APA	Kong, Chang.,Yang, Linsheng.,Yu, Jiangping.,Li, Hairong.,Wei, Binggan.,...&Wu, Kegong.(2020).Changes in urinary arsenic species and methylation capacity in original arsenic exposure cohort after water quality improvement.ENVIRONMENTAL GEOCHEMISTRY AND HEALTH,11.
MLA	Kong, Chang,et al."Changes in urinary arsenic species and methylation capacity in original arsenic exposure cohort after water quality improvement".ENVIRONMENTAL GEOCHEMISTRY AND HEALTH (2020):11.