Comparative Transcriptome Analysis Providing Resistance Mechanism of Aspergillus oryzae Under Arsenate Stress

doi:10.1080/01490451.2021.1877854

	Comparative Transcriptome Analysis Providing Resistance Mechanism of Aspergillus oryzae Under Arsenate Stress
	Liang, Jun 1; Liu, Jing 2,3; Cheng, TingQing 2,5; Song, Wencheng 2,3,4,5
刊名	GEOMICROBIOLOGY JOURNAL
	2021-01-18
关键词	Aspergillus oryzae arsenate comparative transcriptome analysis differentially expressed genes resistance mechanism
ISSN号	0149-0451
DOI	10.1080/01490451.2021.1877854
通讯作者	Cheng, TingQing(chengtq@cmpt.ac.cn) ; Song, Wencheng(wencsong@cmpt.ac.cn)
英文摘要	The molecular resistance mechanism of Aspergillus oryzae (A. oryzae) under arsenate (As(V)) stress was investigated by comparative transcriptome analysis. In total, 4911 differentially expressed genes (DEGs) of A. oryzae were detected under As(V) stress, including 2103 up-regulated genes and 2808 down-regulated genes. Genes induced by As(V) were involved in metal ion binding and transportation, redox homeostasis, efflux carrier, DNA repair, volatilization, etc. Moreover, eight genes were selected for qRT-PCR verification, and their trends were consistent with RNA-Seq analysis, which proved that RNA-Seq analysis was efficient and reliable. The results indicated that the extracellular and intracellular synergistic resistance mechanisms contributed to the improvement of A. oryzae resistance to As (V).
资助项目	National Natural Science Foundation of China[21876179] ; National Natural Science Foundation of China[22006001] ; Natural Science Foundation of Universities of Anhui Province[KJ2019A0914] ; University Outstanding Young Scientific Research Talent Cultivation Program Project in Anhui Province[gxyq2020091]
WOS研究方向	Environmental Sciences & Ecology ; Geology
语种	英语
出版者	TAYLOR & FRANCIS INC
WOS记录号	WOS:000612769900001
资助机构	National Natural Science Foundation of China ; Natural Science Foundation of Universities of Anhui Province ; University Outstanding Young Scientific Research Talent Cultivation Program Project in Anhui Province
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/119814]
专题	中国科学院合肥物质科学研究院
通讯作者	Cheng, TingQing; Song, Wencheng
作者单位	1.Anhui Univ, Jianghuai Coll, Hefei, Peoples R China 2.Chinese Acad Sci, Hefei Inst Phys Sci, Inst Hlth & Med Technol, Anhui Prov Key Lab Med Phys & Technol, Hefei, Peoples R China 3.Chinese Acad Sci, Hefei Canc Hosp, Hefei, Peoples R China 4.Soochow Univ, Collaborat Innovat Ctr Radiat Med, Jiangsu Higher Educ Inst, Suzhou, Peoples R China 5.Soochow Univ, Sch Radiol & Interdisciplinary Sci, Suzhou, Peoples R China
推荐引用方式 GB/T 7714	Liang, Jun,Liu, Jing,Cheng, TingQing,et al. Comparative Transcriptome Analysis Providing Resistance Mechanism of Aspergillus oryzae Under Arsenate Stress[J]. GEOMICROBIOLOGY JOURNAL,2021.
APA	Liang, Jun,Liu, Jing,Cheng, TingQing,&Song, Wencheng.(2021).Comparative Transcriptome Analysis Providing Resistance Mechanism of Aspergillus oryzae Under Arsenate Stress.GEOMICROBIOLOGY JOURNAL.
MLA	Liang, Jun,et al."Comparative Transcriptome Analysis Providing Resistance Mechanism of Aspergillus oryzae Under Arsenate Stress".GEOMICROBIOLOGY JOURNAL (2021).