The stents' adaptability and safety in realistic and idealized stenotic coronary model were compared to investigate the influence of artery geometry parameter on stent fatigue life. The stents' fatigue resistance ability was calculated using Goodman diagram, and the cycle to failure, the fatigue life, and the fatigue safety factor (FSF) were analyzed. Although the peak top of the von Mises stress was located at the bending area of crowns, the stress distributions were different in the two models. Considering the safety and accuracy, it is necessary to use a realistic geometric model to calculate the stent fatigue performance.